{"id":"W2035516863","doi":"10.2217/fmb.14.18","title":"Elucidating Drug Resistance in Human Fungal Pathogens","year":2014,"lang":"en","type":"review","venue":"Future Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Drug resistance; Cryptococcus neoformans; Echinocandin; Echinocandins; Biology; Aspergillus fumigatus; Microbiology; Drug; Cryptococcosis; Candida albicans; Antifungal drug; Aspergillosis; Cryptococcus; Amphotericin B; Immunology; Caspofungin; Antifungal; Fluconazole; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005201388,0.0006868535,0.00131034,0.002762739,0.0002793648,0.001013856,0.0007886186,0.001079326,0.003586043],"category_scores_gemma":[0.0006648014,0.0002807975,0.0005322295,0.001905522,0.0004538194,0.001254903,0.0005886273,0.001301931,0.002145587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005361036,"about_ca_system_score_gemma":0.0008197575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008522057,"about_ca_topic_score_gemma":0.001310876,"domain_scores_codex":[0.9997577,0.00004125844,0.00002982137,0.00003649594,0.0001109997,0.00002374761],"domain_scores_gemma":[0.9997163,0.0001105093,0.00004842488,0.00001072931,0.000090281,0.00002369372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005329689,0.00009595196,0.0003555168,0.01840697,0.00008718132,0.0003489286,0.00009724035,0.0003813211,0.004866307,0.004136325,0.02074372,0.9504272],"study_design_scores_gemma":[0.00001320991,0.00009522069,0.0009600701,0.002546406,0.0001021805,0.001953005,0.00006416488,0.0001289004,0.001672843,0.0016439,0.9908018,0.00001843367],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002397721,0.998138,0.0001530985,0.0001764849,0.00008161446,0.000005498408,0.00001525042,0.000007371083,0.001183046],"genre_scores_gemma":[0.001553055,0.9972522,0.0002411356,0.0001355995,0.0000820152,0.000005467109,0.00003269042,0.000001551695,0.0006962349],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003586043,"threshold_uncertainty_score":0.01199657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878676628068675,"score_gpt":0.3228358596266362,"score_spread":0.3040490933459494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}