{"id":"W2035551117","doi":"10.1111/j.1365-2036.2006.02791.x","title":"CDP571, a humanized monoclonal antibody to tumour necrosis factor‐α, for steroid‐dependent Crohn's disease: a randomized, double‐blind, placebo‐controlled trial","year":2006,"lang":"en","type":"article","venue":"Alimentary Pharmacology & Therapeutics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"UCB Pharma","keywords":"Medicine; Placebo; Prednisone; Crohn's disease; Prednisolone; Azathioprine; Internal medicine; Gastroenterology; Discontinuation; Clinical endpoint; Adverse effect; Randomized controlled trial; Budesonide; Surgery; Corticosteroid; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001754204,0.001153898,0.003024093,0.0004769535,0.0004128215,0.0007176843,0.000801236,0.002138931,0.005080984],"category_scores_gemma":[0.001688371,0.000498026,0.001294859,0.0005069202,0.001244382,0.0006222901,0.0002872063,0.001660516,0.000780102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005366167,"about_ca_system_score_gemma":0.001057894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005725502,"about_ca_topic_score_gemma":0.0008512395,"domain_scores_codex":[0.9993419,0.000344358,0.00006156343,0.0001156545,0.00006687517,0.00006967633],"domain_scores_gemma":[0.9991688,0.0003069662,0.000221997,0.00004319171,0.00004434993,0.0002148349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9736511,0.003722652,0.0005324132,0.001461045,0.0005985526,0.00005424188,0.00003645342,0.0001679059,0.002461036,0.00009005623,0.0007786649,0.01644591],"study_design_scores_gemma":[0.9785761,0.01963085,0.0007929872,0.00003827392,0.0002243491,0.00002996672,0.000006373265,0.0001225191,0.0002188062,0.00003325679,0.000322093,0.00000439878],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644219,0.02499966,0.0008317939,0.001064145,0.0008932453,0.004495173,0.001081294,0.0001550523,0.002057683],"genre_scores_gemma":[0.9718897,0.01443301,0.001658067,0.001436807,0.0008461701,0.006022873,0.001044382,0.00002411701,0.002645017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005080984,"threshold_uncertainty_score":0.01699764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02401346963863357,"score_gpt":0.3321857143600676,"score_spread":0.308172244721434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}