{"id":"W2035555871","doi":"10.1074/jbc.m307388200","title":"A Highly Conserved NTRK3 C-terminal Sequence in the ETV6-NTRK3 Oncoprotein Binds the Phosphotyrosine Binding Domain of Insulin Receptor Substrate-1","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"","keywords":"Terminal (telecommunication); Cell biology; Chemistry; Insulin receptor; Substrate (aquarium); Domain (mathematical analysis); C-terminus; Sequence (biology); Binding site; Receptor; Biology; Insulin; Molecular biology; Biochemistry; Computer science; Amino acid; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000982892,0.0004650087,0.0002849069,0.0002232541,0.0002483788,0.0002258145,0.0002814123,0.0005001549,0.003198216],"category_scores_gemma":[0.0001374295,0.0001350834,0.0004034512,0.000325505,0.0002647844,0.0002193406,0.0002643699,0.0006528514,0.002394228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005839777,"about_ca_system_score_gemma":0.0002824851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008529389,"about_ca_topic_score_gemma":0.00125523,"domain_scores_codex":[0.9998627,0.00002044802,0.00001679206,0.00002519739,0.00005106262,0.00002386465],"domain_scores_gemma":[0.9999212,0.00001077066,0.00003063,0.000008478885,0.000006169392,0.00002273161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002623167,0.00004468415,0.0005954762,0.00006857012,0.00002048339,0.001268727,0.00001460662,0.0002251215,0.9916564,0.0005028243,0.0004094866,0.004931345],"study_design_scores_gemma":[0.0001918816,0.0004538624,0.03491681,0.00002902335,0.0000892219,0.01827671,0.00005189103,0.003119574,0.8805103,0.0005256245,0.06178753,0.0000475145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668492,0.005336551,0.01441236,0.0004705896,0.0003590759,0.0001916966,0.004350757,0.0005576376,0.007472225],"genre_scores_gemma":[0.9779429,0.001285801,0.006336314,0.0002460231,0.00003564179,0.00009094345,0.005273913,0.00007144976,0.008717066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003198216,"threshold_uncertainty_score":0.01069909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0260925446962502,"score_gpt":0.2637590293479141,"score_spread":0.2376664846516639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}