{"id":"W2035650569","doi":"10.1242/bio.2012844","title":"Chromatin remodelling initiation during human spermiogenesis","year":2012,"lang":"en","type":"article","venue":"Biology Open","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lawrence Livermore National Laboratory; Queen's University; Universiteit Utrecht; University of South Carolina; Radboud Universiteit; Friedrich Miescher Institute for Biomedical Research","keywords":"Spermiogenesis; Chromatin; Biology; Cell biology; Acrosome; Spermatid; Histone; Chromatin remodeling; Nucleosome; Protamine; Sperm; Genetics; Nucleus; DNA; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539352,0.00009841056,0.0001284267,0.0004783077,0.0001435424,0.0002545466,0.00008343189,0.00015741,0.003116139],"category_scores_gemma":[0.0002743056,0.0001133752,0.0001244904,0.0002685369,0.0001518448,0.0001576601,0.0001842318,0.0001182902,0.0006820539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001627341,"about_ca_system_score_gemma":0.000146526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008695153,"about_ca_topic_score_gemma":0.001224298,"domain_scores_codex":[0.9998907,0.00002140012,0.000006164904,0.00004111679,0.0000244753,0.00001611719],"domain_scores_gemma":[0.999866,0.0000356857,0.00002932961,0.00001128421,0.00003371486,0.00002397404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00093943,0.00002363852,0.02316234,0.0002386229,0.00002476495,0.0005276605,0.0004001644,0.0002173204,0.950122,0.0003976384,0.0005346434,0.02341181],"study_design_scores_gemma":[0.00003275335,0.0005918491,0.4955698,0.00008712288,0.00003876206,0.001605126,0.0003414198,0.0006878608,0.4680626,0.0002879731,0.03266779,0.00002692727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9561524,0.02298598,0.006693134,0.0001158942,0.00006644354,0.0001079018,0.001926064,0.000243654,0.01170846],"genre_scores_gemma":[0.9916005,0.0021616,0.001047677,0.00005801311,0.00002146737,0.00003887516,0.001252861,0.00001775481,0.003801267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003116139,"threshold_uncertainty_score":0.01042449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03000451519607916,"score_gpt":0.3086163770629564,"score_spread":0.2786118618668772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}