{"id":"W2035716219","doi":"10.1002/biot.201000159","title":"Genome‐scale metabolic modeling of a clostridial co‐culture for consolidated bioprocessing","year":2010,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemostat; Bioprocess; Flux balance analysis; Cellulose; Clostridia; Cellobiose; Chemistry; Microbiology; Flux (metallurgy); Metabolic flux analysis; Biology; Biochemistry; Bioreactor; Metabolism; Bacteria; Genetics; Cellulase; Botany; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002640686,0.0001435744,0.0002145582,0.0001380739,0.0001298558,0.00002006114,0.0002230001,0.0005994627,0.000007235647],"category_scores_gemma":[0.0001383246,0.0001222978,0.0001127685,0.0001358372,0.0001342331,0.000005408685,0.00003531286,0.0004074938,0.000001454984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003721737,"about_ca_system_score_gemma":0.00007971926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003038679,"about_ca_topic_score_gemma":0.000005062659,"domain_scores_codex":[0.9991604,0.00001238364,0.0002867362,0.0002324677,0.00006297868,0.000245044],"domain_scores_gemma":[0.9993792,0.000001268651,0.0001541345,0.000218114,0.0001903096,0.00005695745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006518613,0.00003525654,0.00002988021,0.00001395028,0.00005545781,4.789778e-7,0.00002632431,0.0001502599,0.9972003,0.00008375297,0.000131927,0.002207204],"study_design_scores_gemma":[0.0005226904,0.0001263832,0.00003342631,0.000007017593,0.0000413362,0.0004584813,0.00005027582,0.0003983185,0.9323666,0.00007836978,0.0657796,0.0001375006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683567,0.001785054,0.02871829,0.0003351538,0.0005702207,0.0001293215,0.00004329815,0.00003085136,0.00003113078],"genre_scores_gemma":[0.9844754,0.0006846289,0.01373763,0.00002420153,0.0009282083,0.000005741058,0.00005180695,0.00002002133,0.00007235458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06564768,"threshold_uncertainty_score":0.4987159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006947757561249214,"score_gpt":0.2414144924166229,"score_spread":0.2344667348553737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}