{"id":"W2035759506","doi":"10.1371/journal.pone.0086567","title":"Alternate Reading Frame Protein (F Protein) of Hepatitis C Virus: Paradoxical Effects of Activation and Apoptosis on Human Dendritic Cells Lead to Stimulation of T Cells","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hepatitis C virus research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Fondation pour la Recherche Médicale","keywords":"Biology; Immune system; Cell biology; Antigen; T cell; Acquired immune system; Virology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001414546,0.0001916141,0.0001569629,0.0001039918,0.00008679421,0.0001788707,0.00008678105,0.0002477045,0.0006792089],"category_scores_gemma":[0.0001464492,0.00005788059,0.0001355947,0.00008387566,0.0001435105,0.0001269498,0.0001060836,0.0002393165,0.0002377377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001456126,"about_ca_system_score_gemma":0.00008184444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000197951,"about_ca_topic_score_gemma":0.0001497903,"domain_scores_codex":[0.9998877,0.00002794817,0.000008604994,0.00002348127,0.00002578594,0.00002655127],"domain_scores_gemma":[0.9999257,0.00003086578,0.00001306892,0.000008193576,0.000009115342,0.00001305303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000430072,0.00003208834,0.0005631263,0.00005946243,0.00000477535,0.0001385045,0.00001702714,0.000043268,0.9951305,0.0001181751,0.00006469018,0.003398365],"study_design_scores_gemma":[0.00004505306,0.0008414664,0.008395363,0.000007424045,0.00002518975,0.001984512,0.00002931974,0.0007848731,0.9845094,0.0001761231,0.003196859,0.000004351225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944272,0.003438062,0.001087906,0.00009277587,0.00003597004,0.00001227358,0.0001035731,0.00002370987,0.0007786463],"genre_scores_gemma":[0.9975631,0.001091079,0.0005803684,0.00005213093,0.00002108241,0.000008704014,0.0001161583,0.00000570222,0.0005615973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006792089,"threshold_uncertainty_score":0.002272129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04590184531958397,"score_gpt":0.3037847446824526,"score_spread":0.2578828993628686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}