{"id":"W2035825932","doi":"10.1016/j.toxicon.2013.08.023","title":"Correcting effect of PLA2 subunit of crotoxin on mutated CFTR: Original perspective to investigate the pharmacotherapy of Cystic Fibrosis","year":2013,"lang":"en","type":"article","venue":"Toxicon","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Cystic fibrosis; Pharmacotherapy; Protein subunit; Perspective (graphical); Medicine; Internal medicine; Biology; Genetics; Computer science; Gene; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004959327,0.0001987815,0.0005412903,0.0002277227,0.00004929035,0.00001099987,0.0002030355,0.00005176003,0.0006037248],"category_scores_gemma":[0.00129401,0.0001273145,0.0001156224,0.000574067,0.0003433928,0.00008246634,0.0000402733,0.0002695597,0.00005740526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001297453,"about_ca_system_score_gemma":0.0001167095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001329843,"about_ca_topic_score_gemma":0.00001117424,"domain_scores_codex":[0.9982519,0.0002718562,0.0003951791,0.0002525339,0.0005207401,0.0003078029],"domain_scores_gemma":[0.9971972,0.001703928,0.0002275074,0.0003370964,0.000348659,0.0001856857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002871678,0.0001168577,0.003976976,0.0003322389,0.0001248614,0.000003953777,0.001476238,0.0002731328,0.9827725,0.00005501289,0.0005459698,0.00745062],"study_design_scores_gemma":[0.002075638,0.005928889,0.005623612,0.0006594988,0.00006381273,0.00001975645,0.0005765987,0.001184645,0.98347,0.0001282283,0.0001674182,0.0001019671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963641,0.0002361293,0.0001012516,0.0004143073,0.00009822919,0.001872561,0.00003467831,0.00003084857,0.0008479422],"genre_scores_gemma":[0.9985372,0.000009928302,0.0008716905,0.0001013408,0.00005814044,0.0001170631,0.000005543135,0.00003004089,0.0002690509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007348652,"threshold_uncertainty_score":0.6610363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416211561344225,"score_gpt":0.3423684005948444,"score_spread":0.3282062849814021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}