{"id":"W2035904001","doi":"10.1016/j.vaccine.2014.08.029","title":"Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines","year":2014,"lang":"en","type":"article","venue":"Vaccine","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval; GlaxoSmithKline (Canada); Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs; GlaxoSmithKline","keywords":"Immunogenicity; Virology; Immunization; Inactivated vaccine; Immunology; Titer; Medicine; Antibody; Influenza vaccine; Immune system; Heterologous; Nasal administration; Vaccination; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009786447,0.0009142055,0.0005928012,0.0008006117,0.0002348199,0.0004602895,0.0002921559,0.0005830987,0.001674635],"category_scores_gemma":[0.0005412919,0.0002442002,0.0005659161,0.0001365096,0.0004660395,0.000837287,0.0002310458,0.001473718,0.0003421611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004665563,"about_ca_system_score_gemma":0.0002696143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000692613,"about_ca_topic_score_gemma":0.0007584576,"domain_scores_codex":[0.9996917,0.00007561151,0.00002237277,0.00008619417,0.0000510534,0.00007306015],"domain_scores_gemma":[0.9995236,0.0001216088,0.00009396856,0.00006215012,0.00008381539,0.0001148815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001895888,0.000560455,0.0005212614,0.00006430819,0.00003241424,0.00003644035,0.0000644781,0.00006045604,0.9946884,0.0000967753,0.00006987648,0.001909336],"study_design_scores_gemma":[0.0002638506,0.01359839,0.01391149,0.00003012184,0.0001291337,0.000456486,0.0001166929,0.0005514396,0.9691383,0.0001496785,0.001639478,0.00001493336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975636,0.0005438438,0.0008011283,0.0000736485,0.00006918927,0.00005377613,0.0001232775,0.00003740114,0.0007341804],"genre_scores_gemma":[0.9943674,0.0005026822,0.001254263,0.0001137104,0.00005872672,0.00006158471,0.0004988243,0.0000265928,0.00311622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001674635,"threshold_uncertainty_score":0.005602181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05433583513763664,"score_gpt":0.3327898859932308,"score_spread":0.2784540508555942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}