{"id":"W2035944529","doi":"10.1371/journal.pbio.1001969","title":"A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria","year":2014,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Michael Smith Health Research BC; Canadian Institutes of Health Research; Tula Foundation","keywords":"Cell biology; Endoplasmic reticulum; Mitochondrion; Biology; Phosphatidylethanolamine; Membrane contact site; Translocase of the outer membrane; Mitochondrial membrane transport protein; Inner mitochondrial membrane; Integral membrane protein; Membrane protein; Phospholipid; Biochemistry; Membrane; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001361847,0.0006116781,0.000246054,0.0002666085,0.0001831955,0.0003388142,0.0003356154,0.0004040743,0.0005716978],"category_scores_gemma":[0.0002092802,0.0001567112,0.0002509876,0.0002059426,0.0002448932,0.0002559627,0.0004047749,0.0004292527,0.0003872267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004075053,"about_ca_system_score_gemma":0.000262659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001160284,"about_ca_topic_score_gemma":0.001429007,"domain_scores_codex":[0.9998542,0.000020181,0.00001807013,0.00003885273,0.00005265189,0.00001597245],"domain_scores_gemma":[0.9998165,0.00002329071,0.0000619317,0.00003067924,0.00003451182,0.00003302926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003118136,0.0000147975,0.0003796473,0.00002791313,0.00000602252,0.00005907749,0.00000398438,0.00006462487,0.998292,0.0001045442,0.00003237985,0.0009836883],"study_design_scores_gemma":[0.000007645966,0.0000518286,0.005703719,0.000005056929,0.00001809899,0.0004133086,0.00001772158,0.001084579,0.9903562,0.00003233844,0.002304779,0.000004828172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851133,0.001473419,0.01152566,0.0001721343,0.00003844983,0.00003631508,0.0004634527,0.0002396837,0.000937572],"genre_scores_gemma":[0.9870206,0.0007021637,0.009439895,0.00006176133,0.000005779836,0.00001803903,0.0009304824,0.0000418016,0.001779474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001160284,"threshold_uncertainty_score":0.002956629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02277299926273468,"score_gpt":0.2313069587424052,"score_spread":0.2085339594796705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}