{"id":"W2035966961","doi":"10.1046/j.1440-169x.2003.00705.x","title":"Gene silencing in chick embryos with a vector‐based small interfering RNA system","year":2003,"lang":"en","type":"article","venue":"Development Growth & Differentiation","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"RNA interference; Trans-acting siRNA; Small interfering RNA; Small hairpin RNA; Gene silencing; Biology; Gene; RNA silencing; Electroporation; RNA; Gene expression; Open reading frame; Genetics; Expression vector; Molecular biology; Cell biology; Computational biology; Peptide sequence; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001484118,0.0002214199,0.0001745847,0.0001390303,0.00007654788,0.00004652322,0.0001406251,0.0001120021,0.00001236321],"category_scores_gemma":[0.00002656631,0.0001996842,0.00004214429,0.0001379302,0.00001500665,0.000008818305,0.00003652096,0.00009394244,0.00001339725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001088018,"about_ca_system_score_gemma":0.0001560351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002235734,"about_ca_topic_score_gemma":0.0001564015,"domain_scores_codex":[0.9987761,0.00007679575,0.0003177451,0.0003969021,0.000146684,0.0002857347],"domain_scores_gemma":[0.9995326,0.000008256472,0.0001143323,0.0001878302,0.00009480261,0.00006211094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000146513,0.0001151867,0.05691951,0.0001581403,0.00009103727,0.00001224922,0.0004285901,0.0001919934,0.9408156,0.0001316958,0.0000231749,0.0009662735],"study_design_scores_gemma":[0.0007808164,0.0001222657,0.09441066,0.0001747849,0.00001259651,0.00000962967,0.0001590203,0.0003372568,0.9036675,0.000003761886,0.00004662582,0.0002750933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695712,0.00009940184,0.02918484,0.0000103294,0.0001844644,0.0002083334,0.000002016331,0.00002588688,0.0007135026],"genre_scores_gemma":[0.997723,0.00001127076,0.001802616,0.00006309835,0.00004115482,0.00007850408,0.0001654104,0.00002585903,0.00008903771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03749115,"threshold_uncertainty_score":0.8142884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009679882398065867,"score_gpt":0.1909750507208165,"score_spread":0.1812951683227507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}