{"id":"W2036001221","doi":"10.1067/mpd.2001.118570","title":"A two-year randomized, placebo-controlled trial of dornase alfa in young patients with cystic fibrosis with mild lung function abnormalities","year":2001,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":302,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Medicine; Vital capacity; Placebo; Cystic fibrosis; Adverse effect; Pulmonary function testing; Exacerbation; Internal medicine; Anesthesia; Surgery; Lung; Diffusing capacity; Lung function","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001938654,0.001727812,0.006395743,0.0005164743,0.0007986056,0.001081906,0.001044861,0.003078548,0.004955332],"category_scores_gemma":[0.002795518,0.001011447,0.002334637,0.0004215399,0.001785317,0.001916475,0.000611525,0.003996064,0.001099754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000790498,"about_ca_system_score_gemma":0.001315896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001516065,"about_ca_topic_score_gemma":0.002647112,"domain_scores_codex":[0.9990201,0.0004359148,0.00008582474,0.0001893799,0.00005908687,0.0002097052],"domain_scores_gemma":[0.9984818,0.0004184869,0.0002206786,0.0001263491,0.0001058798,0.0006467529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9931064,0.002449597,0.0002024337,0.0001821126,0.0003708331,0.00002976533,0.00002478538,0.00004676085,0.0007230033,0.00003298988,0.0001875437,0.002643926],"study_design_scores_gemma":[0.9760369,0.02259437,0.0007674181,0.00001075126,0.0002143628,0.00001426469,0.00001766042,0.00006273536,0.0000888095,0.00003628746,0.000148589,0.000007905381],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851769,0.005919074,0.0007411872,0.001458118,0.001797927,0.002605499,0.0007990856,0.0001537153,0.001348471],"genre_scores_gemma":[0.9861088,0.003242866,0.001238143,0.002023678,0.0007671246,0.002959704,0.0009934055,0.00002631762,0.002639944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006395743,"threshold_uncertainty_score":0.01657718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006622360559768427,"score_gpt":0.252869031074789,"score_spread":0.2462466705150206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}