{"id":"W2036050286","doi":"10.1016/j.bbmt.2013.11.032","title":"Does Total Body Irradiation Conditioning Improve Outcomes of Myeloablative Human Leukocyte Antigen–Identical Sibling Transplantations for Chronic Lymphocytic Leukemia?","year":2013,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ottawa Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Takeda Oncology; Osiris Therapeutics; Celgene; U.S. Navy; Genentech; Health Resources and Services Administration; Therakos; Sigma-Tau Pharmaceuticals; Kiadis Pharma; U.S. Department of Defense; Onyx Pharmaceuticals; Medical College of Wisconsin; Tarix Pharmaceuticals; StemCyte; Blue Cross and Blue Shield Association; Swedish Orphan Biovitrum; Teva Pharmaceutical Industries; WellPoint; HistoGenetics; Otsuka America; Amgen; Allos Therapeutics; Ariad Pharmaceuticals; GlaxoSmithKline; Sanofi","keywords":"Medicine; Total body irradiation; Fludarabine; Internal medicine; Chronic lymphocytic leukemia; Transplantation; Sibling; Gastroenterology; Confidence interval; Oncology; Leukemia; Cancer; Immunology; Chemotherapy; Surgery; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002525084,0.000205953,0.0005296028,0.0002858597,0.0001556352,0.00001670489,0.00007754988,0.0002270682,0.000070144],"category_scores_gemma":[0.00006168016,0.0001500319,0.0001509359,0.0001364511,0.0003842222,0.0002322618,0.000008693532,0.0001159212,0.000003000166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001284271,"about_ca_system_score_gemma":0.002337591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001437006,"about_ca_topic_score_gemma":0.0001132492,"domain_scores_codex":[0.9983445,0.0000730549,0.0007073126,0.0003528261,0.0001854859,0.0003368538],"domain_scores_gemma":[0.9987342,0.0005143663,0.0002479412,0.0001564203,0.0002345775,0.0001125175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002323525,0.00005629512,0.01188498,0.001620921,0.0005090544,0.00000683409,0.0009006422,0.00008497677,0.9816624,0.00244828,0.000007122672,0.0005861408],"study_design_scores_gemma":[0.03468212,0.001872907,0.1117242,0.0003945559,0.001623797,0.0001763779,0.0003590972,0.01410662,0.8327922,0.001923457,0.000009814788,0.0003348048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940531,0.0002797726,0.003769131,0.00008930761,0.0001415708,0.001230456,0.0002672153,0.00003955109,0.0001299178],"genre_scores_gemma":[0.9967771,0.0006340135,0.001157625,0.00002957304,0.00009572712,0.0001573666,0.000955118,0.0000225798,0.0001709198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1488702,"threshold_uncertainty_score":0.6118125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163898314724678,"score_gpt":0.2948767863175492,"score_spread":0.2832378031703024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}