{"id":"W2036071626","doi":"10.1083/jcb.200706012","title":"Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility","year":2007,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":291,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Motility; Biology; Cell biology; Myosin; Actin; Myosin light-chain kinase; Actin remodeling; Actin cytoskeleton; Cell; Cytoskeleton; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879684,0.0001852991,0.0002192833,0.00005776737,0.0002665701,0.00002097042,0.000461278,0.0002329068,0.0001580932],"category_scores_gemma":[0.0001116999,0.0001145148,0.0001525696,0.0002133266,0.00006603126,0.000006003942,0.0002407132,0.0003804284,0.00004883264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006539709,"about_ca_system_score_gemma":0.00008357401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007638372,"about_ca_topic_score_gemma":0.0001530361,"domain_scores_codex":[0.998396,0.0003883993,0.0005230996,0.000192365,0.000123587,0.000376546],"domain_scores_gemma":[0.9984711,0.000178876,0.0004924917,0.0004476412,0.000280213,0.0001296572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006490587,0.00008346965,0.0001686295,0.000005850467,0.00003085976,0.00001319207,0.000106691,0.00007613517,0.9967099,0.00002801153,0.001775023,0.0003531376],"study_design_scores_gemma":[0.0004381424,0.0007156786,0.000303099,0.000006883394,0.00007646269,0.0004045436,0.0001500252,0.00002641578,0.9291269,0.0002200117,0.06840938,0.0001224615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738727,0.001228172,0.01913709,0.0003832282,0.0008721328,0.000194701,0.00001362311,0.000005871776,0.004292443],"genre_scores_gemma":[0.9950185,0.000628623,0.0004003276,0.001138412,0.0007051287,7.109926e-7,0.00004481792,0.00002924503,0.002034179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06758305,"threshold_uncertainty_score":0.4669779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006328353598954157,"score_gpt":0.235308361247883,"score_spread":0.2289800076489288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}