{"id":"W2036098781","doi":"10.1074/jbc.c000822200","title":"COUP-TF1 Antagonizes Nkx2.5-mediated Activation of the Calreticulin Gene during Cardiac Development","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Calreticulin; Gene; Medicine; Biology; Cell biology; Genetics; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002373979,0.0001214901,0.0002103655,0.00001378694,0.00007759922,0.000009426868,0.0002798789,0.0002102711,0.00007410527],"category_scores_gemma":[0.0003966202,0.00007134687,0.0001772423,0.0001122528,0.0001370488,0.000003959932,0.000140056,0.0002025641,0.000001750983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003667148,"about_ca_system_score_gemma":0.0001522361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001935598,"about_ca_topic_score_gemma":1.463891e-7,"domain_scores_codex":[0.9989709,0.00005050465,0.0003910629,0.0001502069,0.0002358865,0.0002014665],"domain_scores_gemma":[0.9992235,0.00003700208,0.0002785633,0.0001688399,0.0001989566,0.00009314994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002166414,0.00006439007,0.01582752,0.00001988896,0.00007831024,0.000009451752,0.00001643515,0.00002282703,0.9831731,3.424782e-7,0.00009321026,0.0004778565],"study_design_scores_gemma":[0.0003608964,0.00006714153,0.0226071,0.00003241727,0.0000081105,0.00003239171,0.00007773349,0.000003925753,0.9696973,0.000004018917,0.007016371,0.00009260931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987255,0.0006818015,0.00009787732,0.0001765554,0.00005169235,0.00006091507,0.00001061626,0.000003035213,0.0001919512],"genre_scores_gemma":[0.9983779,0.0007742963,0.000253245,0.00003785361,0.0003260192,0.000003023012,0.00003214702,0.000007403798,0.0001881121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01347584,"threshold_uncertainty_score":0.2909441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01941973375761264,"score_gpt":0.2652440458423096,"score_spread":0.245824312084697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}