{"id":"W2036108773","doi":"10.1309/vqxf-t880-jxc7-qd2w","title":"Activation of the ERK/MAP Kinase Pathway in Cervical Intraepithelial Neoplasia Is Related to Grade of the Lesion but not to High-Risk Human Papillomavirus, Virus Clearance, or Prognosis in Cervical Cancer","year":2004,"lang":"en","type":"article","venue":"American Journal of Clinical Pathology","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cytodiagnostics (Canada)","funders":"Istituto Superiore di Sanità; Ministero della Salute","keywords":"Cervical cancer; Medicine; Cervical intraepithelial neoplasia; Human papillomavirus; Lesion; MAPK/ERK pathway; Kinase; Squamous intraepithelial lesion; Cancer research; Pathology; Virology; Virus; Oncology; Cancer; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001818817,0.0002337741,0.001418477,0.0002921124,0.00007585143,0.000008424937,0.0006120006,0.0002807672,0.0003056069],"category_scores_gemma":[0.001752,0.0001300767,0.0004308471,0.001562951,0.0008640771,0.00007062274,0.000262637,0.002024729,0.000008797697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000241355,"about_ca_system_score_gemma":0.0008064724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004558625,"about_ca_topic_score_gemma":0.002732988,"domain_scores_codex":[0.9946854,0.0011638,0.002392978,0.0004205732,0.0008735063,0.0004638084],"domain_scores_gemma":[0.9970555,0.0006308076,0.001084536,0.0004736472,0.0003960425,0.0003594215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02319688,0.003259954,0.6140549,0.0001672276,0.0001490737,0.0003388288,0.003093101,0.0009933864,0.06537613,0.0004909357,0.0001637046,0.2887159],"study_design_scores_gemma":[0.005118316,0.005790918,0.9316481,0.0004035431,0.00005996205,0.0000484749,0.0003097132,0.00001266899,0.05550518,0.0007311495,0.0002393168,0.0001326696],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753457,0.00004372627,0.0000321829,0.02344286,0.0003428456,0.0006863959,0.00005584306,0.000007063742,0.00004333376],"genre_scores_gemma":[0.9951901,0.0002194205,0.0004416292,0.003802433,0.0002571928,0.00002752597,0.000001158354,0.00003423095,0.0000263279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3175932,"threshold_uncertainty_score":0.8796553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05718652984046637,"score_gpt":0.4142321590380625,"score_spread":0.3570456291975962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}