{"id":"W2036123648","doi":"10.1038/onc.2014.459","title":"IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"National Science Foundation","keywords":"Autophagy; Biology; Gene knockdown; Cell biology; Carcinogenesis; Apoptosis; Programmed cell death; Melanoma; Cancer research; Cell growth; Cell; Biochemistry; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002500794,0.0001526062,0.0004115614,0.0001283297,0.00002788303,0.000004717961,0.00006079391,0.0001083986,0.0001067056],"category_scores_gemma":[0.00005367165,0.0001307284,0.00008246714,0.0001782252,0.00006428042,0.00006822772,0.00003878316,0.00005368707,0.000009421925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005058809,"about_ca_system_score_gemma":0.0001852496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001207445,"about_ca_topic_score_gemma":0.000004128569,"domain_scores_codex":[0.9987822,0.00005700787,0.0003745396,0.0002320468,0.00038997,0.0001642606],"domain_scores_gemma":[0.9990234,0.00003364274,0.000213484,0.0003195308,0.0002062454,0.0002037411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003496599,0.0003356941,0.003454972,0.00009751587,0.000175657,0.00001358073,0.0004804103,0.000004139654,0.9768586,0.0001152204,0.00006097568,0.01805356],"study_design_scores_gemma":[0.002092079,0.0009622735,0.03092145,0.00005902679,0.0001999491,0.00004372884,0.00009977463,0.0002251076,0.9646088,0.000585952,0.00008866366,0.00011316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973291,0.001110106,0.000129654,0.0001378876,0.000142432,0.0003383041,0.00001785043,0.00003691927,0.000757756],"genre_scores_gemma":[0.9985606,0.00004953977,0.0007626751,0.00004511316,0.0001478932,0.00001698462,0.00003037119,0.00002633141,0.0003604667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02746648,"threshold_uncertainty_score":0.5330949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03163886128691722,"score_gpt":0.2840223347116607,"score_spread":0.2523834734247434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}