{"id":"W2036123648","doi":"10.1038/onc.2014.459","title":"IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"National Science Foundation","keywords":"Autophagy; Biology; Gene knockdown; Cell biology; Carcinogenesis; Apoptosis; Programmed cell death; Melanoma; Cancer research; Cell growth; Cell; Biochemistry; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001722824,0.0002883779,0.0002307332,0.0003692133,0.0002421569,0.0003569628,0.0001571948,0.0002653509,0.001545841],"category_scores_gemma":[0.00007738845,0.0001317324,0.0003576647,0.000222481,0.0002330198,0.000270692,0.0002551506,0.001125384,0.0003675889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006445457,"about_ca_system_score_gemma":0.0003221145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007263487,"about_ca_topic_score_gemma":0.001251125,"domain_scores_codex":[0.9998415,0.00002422026,0.00001163453,0.00002918658,0.00002879477,0.00006463708],"domain_scores_gemma":[0.9999422,0.000004557057,0.00001579028,0.00001078235,0.000006900791,0.0000198114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003801725,0.00004253327,0.0005818123,0.00005298512,0.000007774279,0.0000589452,0.00001645512,0.00005806765,0.9968471,0.0003004495,0.0001311671,0.001522681],"study_design_scores_gemma":[0.00004645944,0.0001695738,0.01079038,0.00001390808,0.00003335789,0.0002726628,0.00008406799,0.001159921,0.9821107,0.0001513355,0.005162434,0.000005144669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909464,0.003065316,0.001872175,0.0003533889,0.00007367205,0.00003113429,0.0007948718,0.0001136526,0.002749333],"genre_scores_gemma":[0.9955746,0.0006204309,0.001095397,0.00007240527,0.0000083568,0.00002473402,0.0005484646,0.00001410122,0.002041516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001545841,"threshold_uncertainty_score":0.005171359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03163886128691722,"score_gpt":0.2840223347116607,"score_spread":0.2523834734247434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}