{"id":"W2036138598","doi":"10.1152/ajpcell.00481.2004","title":"Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Myosin light-chain kinase; Depolarization; Rho-associated protein kinase; Phosphorylation; Myosin; Cell biology; Chemistry; Immunoglobulin light chain; Biophysics; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003834508,0.0003249706,0.0005902401,0.0002722233,0.00009567976,0.00001410183,0.0003378914,0.0002564234,0.00007230453],"category_scores_gemma":[0.0001235466,0.0003025493,0.0002041166,0.000423037,0.0003500412,0.00003078379,0.0000939816,0.0003797122,0.00002961337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007619531,"about_ca_system_score_gemma":0.0003032274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004798671,"about_ca_topic_score_gemma":0.00000985247,"domain_scores_codex":[0.9975747,0.0005464116,0.0007782981,0.0004624337,0.0001792221,0.0004588606],"domain_scores_gemma":[0.9981663,0.00005294585,0.001000286,0.0003329031,0.000219858,0.0002277183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004574171,0.0002806791,0.0001277792,0.00002085191,0.00005576457,0.000003690599,0.00012249,0.004378402,0.9920512,0.00002485768,0.0004962949,0.001980569],"study_design_scores_gemma":[0.00143315,0.001068069,0.005797688,0.00005183007,0.00002798198,0.00001446741,0.0001292197,0.00068143,0.9828554,0.0002199665,0.007389545,0.000331207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975189,0.0008905969,0.0004238889,0.0005956978,0.0002252688,0.0002126153,0.00001514658,0.0000142341,0.0001036752],"genre_scores_gemma":[0.9955236,0.0003255148,0.001610629,0.00148358,0.0007501436,0.0000120859,0.0002078325,0.00004139333,0.00004521893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009195758,"threshold_uncertainty_score":0.9999427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004238815452132083,"score_gpt":0.2122223661506489,"score_spread":0.2079835506985168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}