{"id":"W2036237690","doi":"10.1016/s0002-9440(10)63497-9","title":"Down-Regulation of a Novel Actin-Binding Molecule, Skeletrophin, in Malignant Melanoma","year":2003,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Genentech","keywords":"Molecular biology; Biology; Ankyrin repeat; Melanoma; Actin; Immunoprecipitation; Complementary DNA; Gene; Cancer research; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001061319,0.0001630228,0.0002072619,0.0001860902,0.0001907222,0.000200371,0.0001314923,0.000330399,0.0009490467],"category_scores_gemma":[0.0001383385,0.0001516086,0.0001583094,0.00009273541,0.0002072454,0.0001380573,0.0001171902,0.000445529,0.0002184507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002068832,"about_ca_system_score_gemma":0.0001109346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003389513,"about_ca_topic_score_gemma":0.0003789656,"domain_scores_codex":[0.999916,0.00001486883,0.000007212622,0.00001386459,0.00002133781,0.00002664875],"domain_scores_gemma":[0.9999081,0.00001809064,0.00002124631,0.000009094255,0.000008555157,0.00003489494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002581964,0.00001488067,0.0002767099,0.00001068727,0.000002568295,0.0001167504,0.000006462606,0.00001777809,0.9988185,0.00002833514,0.00002399547,0.0004251123],"study_design_scores_gemma":[0.00008506378,0.0009349443,0.03735573,0.000004686501,0.00004609123,0.00172401,0.00007997156,0.001306279,0.9559904,0.00009982278,0.002367835,0.000005370513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982978,0.0008459963,0.0003430431,0.00006278453,0.00002395187,0.000005007078,0.00005257905,0.00001724648,0.0003517278],"genre_scores_gemma":[0.9986598,0.0002711265,0.0001808379,0.00002041208,0.000006947419,0.000007966988,0.00006922305,0.000003847744,0.0007798637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009490467,"threshold_uncertainty_score":0.003174901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008832187423879829,"score_gpt":0.2491637529132222,"score_spread":0.2403315654893424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}