{"id":"W2036258026","doi":"10.1021/pr300139q","title":"Quantitative Metabolomic Profiling of Serum, Plasma, and Urine by <sup>1</sup> H NMR Spectroscopy Discriminates between Patients with Inflammatory Bowel Disease and Healthy Individuals","year":2012,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":246,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Calgary","funders":"Oesterreichische Nationalbank; Fondation pour la Recherche Médicale; Genome Alberta; Austrian Science Fund; Deutsche Forschungsgemeinschaft; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation; University of Calgary","keywords":"Urine; Metabolomics; Ulcerative colitis; Chemistry; Allantoin; Metabolome; Inflammatory bowel disease; Internal medicine; Blood proteins; Betaine; Crohn's disease; Chromatography; Medicine; Biochemistry; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004737461,0.0003884803,0.0003894732,0.0004985131,0.0001937751,0.0003567119,0.0001174351,0.0003296834,0.0006592429],"category_scores_gemma":[0.0006004093,0.0001091958,0.000199994,0.0004963715,0.0002920567,0.0001600269,0.0001949072,0.000292155,0.0002276449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001355553,"about_ca_system_score_gemma":0.0001805377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000543235,"about_ca_topic_score_gemma":0.0009312605,"domain_scores_codex":[0.9996682,0.0001055699,0.00002920759,0.00009623603,0.00005756229,0.00004314877],"domain_scores_gemma":[0.9996332,0.0001127194,0.0001009462,0.00004035814,0.00007186271,0.00004093064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001797767,0.0001135759,0.03959758,0.0001517309,0.000119127,0.00007903982,0.00009849056,0.0002953357,0.9356702,0.00007274237,0.000257134,0.02174729],"study_design_scores_gemma":[0.00005054199,0.001905036,0.5635072,0.00003048544,0.0002886654,0.00110597,0.0002873021,0.006893624,0.4231858,0.0004093235,0.002285669,0.00005030564],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821552,0.002409676,0.01232795,0.0001448454,0.00002233041,0.00005877436,0.001935386,0.0001608155,0.000785057],"genre_scores_gemma":[0.97677,0.0008173792,0.01953897,0.0001919984,0.00002868536,0.0001028672,0.001971746,0.00002799448,0.0005503791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006592429,"threshold_uncertainty_score":0.002505481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02571193499632185,"score_gpt":0.3257974212748372,"score_spread":0.3000854862785153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}