{"id":"W2036315589","doi":"10.1021/ol902322r","title":"Boron-Catalyzed Direct Aldol Reactions of Pyruvic Acids","year":2009,"lang":"en","type":"article","venue":"Organic Letters","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Aldol reaction; Boron; Catalysis; Organic chemistry; Pyruvic acid; Boronic acid; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002675389,0.0007473814,0.0003853922,0.0003607061,0.0002715349,0.0003800695,0.0004262503,0.0003611296,0.002532602],"category_scores_gemma":[0.0002779671,0.0003037717,0.0003265973,0.0002339899,0.0002468468,0.0005242907,0.0006722602,0.0008102336,0.001441589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004196963,"about_ca_system_score_gemma":0.000263551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004712289,"about_ca_topic_score_gemma":0.001159118,"domain_scores_codex":[0.9997379,0.00003887512,0.00001565015,0.00004055215,0.00006391686,0.0001031193],"domain_scores_gemma":[0.9999005,0.00001662031,0.00001913935,0.00001441634,0.00001833156,0.00003093744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001924475,0.000083275,0.0002187993,0.000446899,0.00004523759,0.0003630758,0.0001698719,0.0007779162,0.9770996,0.004193063,0.0004885996,0.01592124],"study_design_scores_gemma":[0.00001986333,0.00008741524,0.0001251745,0.000004905989,0.000009875708,0.0001181027,0.00001258459,0.0002825595,0.9935911,0.0002055196,0.005533479,0.000009416728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8942631,0.009277565,0.05317879,0.0004397338,0.0004666882,0.000250174,0.0006305444,0.0006832544,0.04081006],"genre_scores_gemma":[0.9745303,0.003387988,0.01060772,0.00006978255,0.00003714205,0.00004587214,0.0002464751,0.00006014789,0.01101453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002532602,"threshold_uncertainty_score":0.008472383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007064124044030281,"score_gpt":0.2061714323586123,"score_spread":0.199107308314582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}