{"id":"W2036362984","doi":"10.1016/j.jim.2011.09.008","title":"Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells","year":2011,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Antigen; Biology; CD8; Ex vivo; T cell; Antigen-presenting cell; Cytolysis; Cytotoxicity; Cell biology; Immunology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003872265,0.0006201764,0.0004289181,0.0001839876,0.000167263,0.000475692,0.0002120212,0.0004861636,0.001670454],"category_scores_gemma":[0.0003407617,0.000133932,0.0002813884,0.0001904682,0.0002201565,0.0003270282,0.0001676067,0.001303625,0.0004839039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001700189,"about_ca_system_score_gemma":0.0001769512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001201628,"about_ca_topic_score_gemma":0.0001331436,"domain_scores_codex":[0.9996941,0.00007861435,0.00002951124,0.00006534705,0.00005627044,0.0000762104],"domain_scores_gemma":[0.9995422,0.0002419694,0.00002828527,0.0001045407,0.00004060179,0.00004238458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000604652,0.0001502994,0.0002606706,0.00003933606,0.000008827697,0.00003552768,0.00002063824,0.0001340294,0.9973131,0.00005160607,0.00002821949,0.001353085],"study_design_scores_gemma":[0.00005551387,0.001135343,0.001684957,0.000003774961,0.00002093139,0.0001506948,0.00001724488,0.00070051,0.9959182,0.00004906708,0.0002607471,0.000003045048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944892,0.00104829,0.002974769,0.00003609048,0.00005846846,0.00003370914,0.000305244,0.00006089947,0.0009933653],"genre_scores_gemma":[0.9962161,0.000384881,0.001157342,0.00004094494,0.00003315193,0.00005263415,0.0005406053,0.00001474343,0.001559492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001670454,"threshold_uncertainty_score":0.005588233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1126969241470215,"score_gpt":0.2945628822660049,"score_spread":0.1818659581189834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}