{"id":"W2036365736","doi":"10.1158/1538-7445.am10-3207","title":"Abstract 3207: Telomerase inhibition affects fludarabine sensitivity in quiescent primary chronic lymphocytic leukemia lymphocytes","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Parks Canada; McGill University","funders":"","keywords":"Telomerase; Chronic lymphocytic leukemia; Fludarabine; Telomere; Medicine; Cancer; Cancer research; Leukemia; Shelterin; Immunology; Oncology; Internal medicine; Biology; Chemotherapy; Genetics; DNA; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296481,0.0002281895,0.0004360596,0.0002141198,0.000157552,0.000350612,0.0002498788,0.0003175878,0.002990184],"category_scores_gemma":[0.0002198131,0.0001116346,0.000211615,0.0001551122,0.0001629145,0.0001242325,0.0001159937,0.0004540735,0.0005088669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003225493,"about_ca_system_score_gemma":0.0002074257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008698999,"about_ca_topic_score_gemma":0.001003727,"domain_scores_codex":[0.9997709,0.00006535344,0.00002380659,0.00003510998,0.00003758939,0.0000672229],"domain_scores_gemma":[0.9998197,0.00007069366,0.00002003147,0.00001980507,0.00002220125,0.00004762665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001240588,0.0003905656,0.0009963779,0.00006449904,0.00001880928,0.00009487791,0.00003572668,0.0001222959,0.9909288,0.00005044668,0.000318831,0.00573822],"study_design_scores_gemma":[0.0006608328,0.01536117,0.0313366,0.00002540804,0.0001000784,0.0008732012,0.0000718286,0.001252931,0.9457752,0.00006519506,0.004465027,0.00001250586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967853,0.001680196,0.0001988924,0.00004858943,0.00003410113,0.00003010307,0.0002778903,0.00003309368,0.0009119038],"genre_scores_gemma":[0.9971841,0.0004377311,0.0002725004,0.00005851596,0.00002110325,0.00004220909,0.0005691189,0.00001214171,0.001402416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002990184,"threshold_uncertainty_score":0.01000315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03269344125154808,"score_gpt":0.364059816966657,"score_spread":0.3313663757151089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}