{"id":"W2036436704","doi":"10.1006/geno.2000.6282","title":"Succinyl-CoA:3-Ketoacid CoA Transferase (SCOT): Cloning of the Human SCOT Gene, Tertiary Structural Modeling of the Human SCOT Monomer, and Characterization of Three Pathogenic Mutations","year":2000,"lang":"en","type":"article","venue":"Genomics","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Ministry of Education, Culture, Sports, Science and Technology; Ono Medical Research Foundation; Juvenile Diabetes Research Foundation United States of America","keywords":"Biology; Transferase; Missense mutation; Gene; Locus (genetics); Molecular biology; Exon; Homology (biology); Genetics; Biochemistry; Enzyme; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001038529,0.0005756774,0.0001681777,0.0002253087,0.0001911887,0.0002071236,0.0002061845,0.0003987116,0.0007501956],"category_scores_gemma":[0.0002228587,0.0001215053,0.0002628301,0.0001689919,0.0003494914,0.0001267388,0.0001915591,0.0004191739,0.0003784676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004309139,"about_ca_system_score_gemma":0.0003221722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001685098,"about_ca_topic_score_gemma":0.001513392,"domain_scores_codex":[0.9999466,0.000006381431,0.000006169925,0.00001372119,0.00001683426,0.00001031516],"domain_scores_gemma":[0.9998852,0.00002277866,0.00002388345,0.000008073038,0.00001352783,0.00004658192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007653346,0.00005972418,0.003450588,0.00005944347,0.00001681061,0.004297503,0.00007031566,0.0006368152,0.9854164,0.0005197505,0.0002206917,0.004486762],"study_design_scores_gemma":[0.00006783058,0.0004182355,0.02515727,0.00001225294,0.00004089558,0.01069888,0.00007732707,0.003918773,0.9563357,0.0004099281,0.002850116,0.00001270174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938812,0.0003244184,0.00467103,0.0001955414,0.00002422175,0.00002109933,0.0003800794,0.00007767395,0.0004247658],"genre_scores_gemma":[0.9955601,0.0002545099,0.002460841,0.000030345,0.000008399326,0.000008095553,0.0007730536,0.00001683958,0.0008878822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001685098,"threshold_uncertainty_score":0.003350556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01237456743971893,"score_gpt":0.2399377913575893,"score_spread":0.2275632239178703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}