{"id":"W2036449665","doi":"10.4161/auto.27785","title":"PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Biology; Parkin; Chromosomal translocation; Proteasome; Atrophy; Cell biology; Mitochondrion; Genetics; Internal medicine; Parkinson's disease; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009456254,0.0001920715,0.000198708,0.00005875998,0.000183666,0.00002389234,0.0001985541,0.000231176,0.00003253897],"category_scores_gemma":[0.000152983,0.0002011395,0.00009243086,0.0001555052,0.00006631558,0.00001425273,0.00004522158,0.0001216141,0.0001025252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001983697,"about_ca_system_score_gemma":0.00003237104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000389043,"about_ca_topic_score_gemma":0.00001246169,"domain_scores_codex":[0.9987281,0.0001195433,0.0002412837,0.000470108,0.0001138867,0.0003271057],"domain_scores_gemma":[0.9993454,0.00002316587,0.00009171224,0.0003559152,0.00008649957,0.0000972667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007135189,0.00007728316,0.00007295245,0.00002415645,0.00004287236,4.118304e-7,0.00007959781,0.0003180042,0.9933977,0.0001813503,0.0004131134,0.004679018],"study_design_scores_gemma":[0.00345447,0.0005627523,0.1375204,0.00004358691,0.00002558675,0.00000184904,0.00003151138,0.0009271285,0.8070818,0.0005446084,0.04933582,0.000470491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895871,0.0000945685,0.008506778,0.0006794731,0.0002863336,0.000534155,0.000007117824,0.00006067052,0.0002437786],"genre_scores_gemma":[0.9978207,0.00002904073,0.000302394,0.001091239,0.000369404,0.000105111,0.0001339053,0.00003557418,0.0001126015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1863159,"threshold_uncertainty_score":0.8202232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003444255823110201,"score_gpt":0.2016703624084225,"score_spread":0.1982261065853123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}