{"id":"W2036449946","doi":"10.1016/j.eururo.2013.08.007","title":"Initial Biopsy Gleason Score as a Predictive Marker for Survival Benefit in Patients with Castration-resistant Prostate Cancer Treated with Docetaxel: Data from the TAX327 Study","year":2013,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Docetaxel; Medicine; Prostate cancer; Mitoxantrone; Oncology; Internal medicine; Cabazitaxel; Prednisone; Cancer; Androgen deprivation therapy; Urology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271774,0.0003888427,0.0009529478,0.0004578433,0.0001712051,0.0007316278,0.0003421778,0.0004640871,0.0008260506],"category_scores_gemma":[0.002503937,0.0002220824,0.0011639,0.0008915977,0.0003266531,0.0003975878,0.0002482131,0.0007857329,0.0001298798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005425336,"about_ca_system_score_gemma":0.000681076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004144092,"about_ca_topic_score_gemma":0.01024476,"domain_scores_codex":[0.9995091,0.0002412296,0.00003860214,0.00006320969,0.00008907553,0.00005869268],"domain_scores_gemma":[0.998341,0.0006724773,0.0004957976,0.0001288123,0.00009225785,0.000269741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.08352935,0.000622606,0.8604361,0.0003702932,0.003519841,0.0002701085,0.0001239007,0.002264027,0.002386732,0.0001846731,0.002939453,0.04335295],"study_design_scores_gemma":[0.003228033,0.00322803,0.9874401,0.00006925123,0.002678117,0.0002442344,0.00007389815,0.0009754902,0.0003419921,0.0002426371,0.001448653,0.00002944072],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912334,0.006169355,0.00008954858,0.0002480257,0.000037256,0.00002361059,0.001132131,0.000008461258,0.001058318],"genre_scores_gemma":[0.997178,0.001127964,0.00006633621,0.000105579,0.00004093557,0.000008618582,0.001282372,0.00000405147,0.0001860974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004144092,"threshold_uncertainty_score":0.008239985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04290832817882424,"score_gpt":0.3075636299090859,"score_spread":0.2646553017302616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}