{"id":"W2036449946","doi":"10.1016/j.eururo.2013.08.007","title":"Initial Biopsy Gleason Score as a Predictive Marker for Survival Benefit in Patients with Castration-resistant Prostate Cancer Treated with Docetaxel: Data from the TAX327 Study","year":2013,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Docetaxel; Medicine; Prostate cancer; Mitoxantrone; Oncology; Internal medicine; Cabazitaxel; Prednisone; Cancer; Androgen deprivation therapy; Urology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002451376,0.0002408661,0.0003008606,0.0000716834,0.0001247307,0.00005371568,0.0002738625,0.00003725003,0.0002205351],"category_scores_gemma":[0.00006488798,0.0001232533,0.00002109918,0.0002312952,0.0002012349,0.0001733504,0.0001313742,0.0002417175,0.00003905099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007389118,"about_ca_system_score_gemma":0.0001911844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003854048,"about_ca_topic_score_gemma":0.00258428,"domain_scores_codex":[0.9981384,0.0002571372,0.0002518136,0.0006191933,0.0003261501,0.0004072975],"domain_scores_gemma":[0.9986623,0.0001769206,0.000120064,0.0006260623,0.0002977342,0.0001169512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03219991,0.0007793554,0.9635478,0.00001433434,0.0004983615,0.0002179462,0.0008250923,0.00001924305,0.0001151551,0.00000362865,0.0004355041,0.001343634],"study_design_scores_gemma":[0.01581347,0.00933032,0.9733714,0.0000675134,0.0002532439,0.000004213296,0.0004715455,0.0001485616,0.00002818845,0.000008902635,0.0003684663,0.000134181],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917955,0.0002583143,0.000006690773,0.0009681831,0.00006543258,0.004685041,0.001232835,0.00003812714,0.000949905],"genre_scores_gemma":[0.9969375,0.00002730063,0.0000501678,0.0001686232,0.0001376535,0.0003782855,0.001787708,0.00006526992,0.000447499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01638644,"threshold_uncertainty_score":0.5826192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04290832817882424,"score_gpt":0.3075636299090859,"score_spread":0.2646553017302616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}