{"id":"W2036473416","doi":"10.1359/jbmr.2003.18.2.237","title":"Positive Linear Growth and Bone Responses to Growth Hormone Treatment in Children With Types III and IV Osteogenesis Imperfecta: High Predictive Value of the Carboxyterminal Propeptide of Type I Procollagen","year":2003,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"Core Research for Evolutional Science and Technology; National Institutes of Health","keywords":"Medicine; Endocrinology; Internal medicine; Iliac crest; Osteocalcin; Osteogenesis imperfecta; Bone age; Bone remodeling; Cancellous bone; Type I collagen; Bone density; Procollagen peptidase; Alkaline phosphatase; Surgery; Biology; Osteoporosis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000668726,0.0001159744,0.0002832428,0.0002264068,0.00006211091,0.00001258957,0.00006697177,0.00006638718,0.0000014806],"category_scores_gemma":[0.0006794701,0.00007048835,0.00003317722,0.0003242179,0.0002514614,0.00001126501,0.0001099826,0.0001295804,6.820468e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002758104,"about_ca_system_score_gemma":0.0003599442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008377259,"about_ca_topic_score_gemma":0.0001385949,"domain_scores_codex":[0.9986449,0.0003871465,0.0002398462,0.0002012283,0.0003130953,0.000213763],"domain_scores_gemma":[0.9989549,0.00008395079,0.00009557467,0.0001114461,0.0006492648,0.0001048451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006510773,0.000168514,0.1693505,0.0000317233,0.0001904628,0.00002031524,0.0005609653,0.000005305104,0.8222965,0.00004624317,0.00003646083,0.0007822489],"study_design_scores_gemma":[0.002486921,0.01354132,0.6139508,0.00008207124,0.00004704455,0.0002718467,0.0004583114,0.000008671913,0.3689935,0.00004231941,0.00002450241,0.000092726],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943633,0.004568034,0.000004154417,0.0002384464,0.000005244091,0.0007198888,0.00002394688,5.298532e-7,0.00007644019],"genre_scores_gemma":[0.9977767,0.001618705,0.0002202405,0.000007725913,0.00003510011,0.00001832644,0.000002376114,0.00001303111,0.0003078328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.453303,"threshold_uncertainty_score":0.2874431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246190539879904,"score_gpt":0.2935114918400811,"score_spread":0.281049586441282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}