{"id":"W2036497729","doi":"10.1055/s-2006-946909","title":"Inhibitor Development in Hemophiliacs: The Roles of Genetic versus Environmental Factors","year":2006,"lang":"en","type":"review","venue":"Seminars in Thrombosis and Hemostasis","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Major histocompatibility complex; Disease; Immune system; Immunology; Allele; Mutation; Antibody; Medicine; Gene; Risk factor; Histocompatibility; Genetics; Biology; Human leukocyte antigen; Antigen; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006424112,0.0008227783,0.002464682,0.001806459,0.0002322499,0.001018931,0.0008598972,0.001208134,0.002320625],"category_scores_gemma":[0.0007913625,0.0002189795,0.000411387,0.002278135,0.0006115137,0.001094178,0.000429311,0.001050426,0.001506524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005067835,"about_ca_system_score_gemma":0.0007030258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001095179,"about_ca_topic_score_gemma":0.001540921,"domain_scores_codex":[0.9997626,0.000060612,0.00003306287,0.00003764608,0.00008763032,0.00001849302],"domain_scores_gemma":[0.9996406,0.0001980415,0.00005743168,0.000008724604,0.00006380491,0.00003147206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009485438,0.00004421549,0.0005239578,0.01089504,0.0001010883,0.0005066671,0.00006282899,0.0001516156,0.0006385462,0.001283617,0.01299292,0.9727045],"study_design_scores_gemma":[0.00009538163,0.0002930887,0.007508782,0.01110926,0.0004710092,0.01437155,0.0003087178,0.000155097,0.0008305767,0.003130541,0.9616789,0.00004705838],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001052488,0.9993914,0.00004317703,0.0001120855,0.00003617388,0.000001033451,0.000004074248,0.000002508543,0.0003042043],"genre_scores_gemma":[0.0006716616,0.998957,0.00007081084,0.00005322904,0.00006450488,0.000002117647,0.000008381713,5.199763e-7,0.0001717919],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002464682,"threshold_uncertainty_score":0.007763267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0798648161696313,"score_gpt":0.3555497360068792,"score_spread":0.2756849198372479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}