{"id":"W2036507745","doi":"10.1016/j.ijpharm.2012.02.032","title":"Carboxymethyl starch: Chitosan monolithic matrices containing diamine oxidase and catalase for intestinal delivery","year":2012,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Catalase; Diamine oxidase; Chitosan; Hydrogen peroxide; Chemistry; Enzyme; Glucose oxidase; Immobilized enzyme; Biochemistry; Nuclear chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002104295,0.0003628534,0.0002120513,0.0002017234,0.00009906427,0.000250355,0.0001896861,0.0003822077,0.0004627524],"category_scores_gemma":[0.0002084764,0.0002004828,0.0001936632,0.0001174223,0.0001445747,0.0002249622,0.000126018,0.0003949342,0.0001389619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002230573,"about_ca_system_score_gemma":0.0001961389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005598955,"about_ca_topic_score_gemma":0.001116107,"domain_scores_codex":[0.9998981,0.00001253332,0.000008138082,0.00003140245,0.0000308687,0.00001905661],"domain_scores_gemma":[0.9998418,0.00003610738,0.00005408633,0.000009163183,0.00002769883,0.00003115872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002840644,0.000008171712,0.00002471447,0.00002655456,0.000002531258,0.00001846132,0.000003714533,0.00002543655,0.9988403,0.00001569718,0.00001156499,0.000994465],"study_design_scores_gemma":[0.00001497631,0.0005352828,0.001116573,0.000005906096,0.0000258491,0.0001409334,0.000008105933,0.000656152,0.9964783,0.000009518145,0.001002213,0.000006134976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848613,0.003959777,0.009681444,0.00008146927,0.00005941588,0.00008978711,0.0001235163,0.0001369127,0.001006467],"genre_scores_gemma":[0.9874982,0.001421588,0.009749928,0.00004300155,0.00001912527,0.00004732738,0.0001502341,0.00001854293,0.001052094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005598955,"threshold_uncertainty_score":0.001618385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03693879178813637,"score_gpt":0.3556677718514053,"score_spread":0.3187289800632689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}