{"id":"W2036507877","doi":"10.1089/152308604322899422","title":"Distinct Roles of Ca <sup>2+</sup> , Calmodulin, and Protein Kinase C in H <sub>2</sub> O <sub>2</sub> -Induced Activation of ERK1/2, p38 MAPK, and Protein Kinase B Signaling in Vascular Smooth Muscle Cells","year":2004,"lang":"en","type":"article","venue":"Antioxidants and Redox Signaling","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Phosphorylation; MAPK/ERK pathway; Protein kinase A; p38 mitogen-activated protein kinases; Protein kinase B; Kinase; Protein kinase C; Calmodulin; Chemistry; BAPTA; Cell biology; Molecular biology; Biology; Biochemistry; Extracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002426871,0.0004656015,0.0005704867,0.0003354796,0.0003312913,0.0004821807,0.0004599612,0.0006204794,0.0008874718],"category_scores_gemma":[0.0002040165,0.000371272,0.0004164367,0.00018146,0.0004503969,0.0005513101,0.0004104287,0.0006724307,0.0002237622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004965511,"about_ca_system_score_gemma":0.0004639091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001361167,"about_ca_topic_score_gemma":0.002322397,"domain_scores_codex":[0.9997675,0.00003262157,0.00001730968,0.00003950543,0.00005577219,0.00008736439],"domain_scores_gemma":[0.9998405,0.00001389972,0.00003541175,0.000008981895,0.00002341465,0.00007784076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007367201,0.00007587745,0.0003145069,0.0001157338,0.00001121283,0.0001877693,0.0000530898,0.00005108611,0.9965709,0.0003955748,0.00007346024,0.001414026],"study_design_scores_gemma":[0.0008816198,0.001600603,0.1334708,0.00006638616,0.0001399394,0.001062799,0.0003464886,0.008404204,0.8455907,0.001132354,0.00724932,0.00005482217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803192,0.01218093,0.003162677,0.0004430917,0.0001114129,0.0001406356,0.0002823352,0.00006922493,0.003290562],"genre_scores_gemma":[0.9918054,0.002758967,0.002266911,0.0001956434,0.00007327571,0.0002424459,0.000249864,0.00001320644,0.002394172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001361167,"threshold_uncertainty_score":0.003602743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007670914172095521,"score_gpt":0.2123647379292897,"score_spread":0.2046938237571942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}