{"id":"W2036595310","doi":"10.1128/jvi.03076-13","title":"Morbillivirus Control of the Interferon Response: Relevance of STAT2 and mda5 but Not STAT1 for Canine Distemper Virus Virulence in Ferrets","year":2013,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virology and Viral Diseases","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; MDA5; Virology; Measles virus; Canine distemper; Morbillivirus; STAT2; Interferon; Innate immune system; Paramyxoviridae; Virus; STAT protein; Immune system; Immunology; Signal transduction; Cell biology; Vaccination; Measles; Viral disease; Genetics; RNA interference; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001288068,0.0003038255,0.0001762847,0.0002152917,0.000147034,0.0002340332,0.0001437245,0.0003638465,0.0007286443],"category_scores_gemma":[0.0001130996,0.00006485872,0.0002125774,0.00004952158,0.0003257754,0.0001874262,0.0001409715,0.0003248165,0.0001532527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004868356,"about_ca_system_score_gemma":0.0001412183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004813931,"about_ca_topic_score_gemma":0.0006074145,"domain_scores_codex":[0.9998971,0.00001536105,0.00001060257,0.00002873782,0.00001944664,0.00002872859],"domain_scores_gemma":[0.9999163,0.00001412017,0.00003331892,0.000007041084,0.000007364047,0.00002172011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002266712,0.0000220275,0.001564123,0.00002361207,0.00000368604,0.00006220181,0.0000207545,0.00005306741,0.9971392,0.00004739069,0.00002711644,0.0008101215],"study_design_scores_gemma":[0.00005209893,0.0008118157,0.06555219,0.0000190471,0.00004491354,0.001265682,0.0001681615,0.001575826,0.9283168,0.0001663786,0.00201677,0.00001032942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984542,0.0006195848,0.0003819214,0.00004433724,0.00001043541,0.00001065942,0.0001499621,0.0000180831,0.0003107778],"genre_scores_gemma":[0.9987923,0.0001274356,0.0003238599,0.0000243844,0.000005422066,0.00001936291,0.0002009295,0.000004614176,0.000501594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007286443,"threshold_uncertainty_score":0.003532231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549268419002294,"score_gpt":0.2884350318498575,"score_spread":0.2729423476598346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}