{"id":"W2036595545","doi":"10.1016/j.ijrobp.2005.08.012","title":"Preoperative radiation with concurrent chemotherapy for resectable rectal cancer: Effect of dose escalation on pathologic complete response, local recurrence-free survival, disease-free survival, and overall survival","year":2005,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Radiation therapy; Clinical endpoint; Toxicity; Chemotherapy; Rectum; Internal medicine; Acute toxicity; Cohort; Adenocarcinoma; Surgery; Gastroenterology; Cancer; Oncology; Urology; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001469751,0.0003725871,0.0009653122,0.0002080956,0.0001111118,0.00003305292,0.0003858542,0.0002219236,0.00006159743],"category_scores_gemma":[0.001265507,0.0002798887,0.0002499218,0.0002219066,0.0003857979,0.0003221452,0.00007992586,0.0004358099,0.00000284426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001540508,"about_ca_system_score_gemma":0.0007061187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004729563,"about_ca_topic_score_gemma":0.00005481572,"domain_scores_codex":[0.9966951,0.001066381,0.0008251803,0.0004566795,0.0006383077,0.0003183318],"domain_scores_gemma":[0.9942484,0.003103222,0.001149661,0.0002957741,0.0009656447,0.0002372453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1263286,0.001243434,0.4774123,0.00008475777,0.001563907,0.00005811876,0.0006139539,0.004666509,0.002715611,0.004135113,0.001072016,0.3801057],"study_design_scores_gemma":[0.1011145,0.04469416,0.8032715,0.0006592414,0.0008012706,0.0001178207,0.0001015161,0.01688746,0.009179879,0.004274127,0.01813025,0.0007682613],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829106,0.001266838,0.006163686,0.005480469,0.001870477,0.00124461,0.0007708524,0.00003853767,0.0002538839],"genre_scores_gemma":[0.995562,0.00159894,0.0008437151,0.0002252926,0.001317025,0.0001279879,0.0002352433,0.00004193095,0.00004789775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3793374,"threshold_uncertainty_score":0.9999653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03125309668657998,"score_gpt":0.3517282160007646,"score_spread":0.3204751193141846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}