{"id":"W2036600184","doi":"10.1016/j.jhep.2014.07.014","title":"Liver sinusoidal endothelial dysfunction after LPS administration: A role for inducible-nitric oxide synthase","year":2014,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Endothelial dysfunction; Nitric oxide synthase; Liver injury; Endocrinology; Medicine; Internal medicine; Nitric oxide; Enos; Lipopolysaccharide; Microcirculation; Downregulation and upregulation; Sepsis; Liver function; Pharmacology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003370735,0.0004332319,0.0005097579,0.0002064355,0.0001760003,0.0003013946,0.0001915843,0.0005658096,0.001879887],"category_scores_gemma":[0.0004309507,0.0001817391,0.0003044402,0.0001356458,0.00050253,0.0004898693,0.0002703399,0.001118663,0.0001858683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002082956,"about_ca_system_score_gemma":0.0002625836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001681024,"about_ca_topic_score_gemma":0.0002526673,"domain_scores_codex":[0.9998714,0.00004674759,0.00001185577,0.00001290107,0.00002348187,0.00003371518],"domain_scores_gemma":[0.9995564,0.00006506258,0.0001575059,0.00005863,0.00003655671,0.0001258468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03646667,0.0007540499,0.007368845,0.0004174958,0.0001019969,0.004253097,0.0001648869,0.0002316526,0.932934,0.000556986,0.0002910667,0.01645922],"study_design_scores_gemma":[0.00119071,0.01321633,0.3357051,0.0001319134,0.0005095199,0.005105671,0.0007793688,0.003416375,0.635506,0.001389989,0.002981657,0.0000672625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935667,0.001955258,0.002761601,0.0004445912,0.00009762596,0.00003099142,0.00008287462,0.00006059508,0.0009998027],"genre_scores_gemma":[0.9977182,0.0005909692,0.000705338,0.0001123317,0.00007828401,0.0000295471,0.00006715216,0.000007172582,0.0006909667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001879887,"threshold_uncertainty_score":0.006288886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01277086882351672,"score_gpt":0.2594221568765371,"score_spread":0.2466512880530204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}