{"id":"W2036644772","doi":"10.1182/blood-2007-11-123885","title":"A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Bone and Joint Diseases","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; National Institute of General Medical Sciences; American Lebanese Syrian Associated Charities; McGill University","keywords":"Internal medicine; Odds ratio; Medicine; Genotype; Oncology; Acute lymphocytic leukemia; Univariate analysis; Gastroenterology; Methylenetetrahydrofolate reductase; Leukemia; Lymphoblastic Leukemia; Multivariate analysis; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293101,0.0003083059,0.000597389,0.0001050122,0.0001600133,0.00001603531,0.0001780474,0.0002108224,0.00008522051],"category_scores_gemma":[0.0001402952,0.0001984514,0.0001522706,0.0003630905,0.0002813421,0.0001084581,0.00009996333,0.0003421134,0.00004348954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001580246,"about_ca_system_score_gemma":0.0009422064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004902087,"about_ca_topic_score_gemma":0.0004092585,"domain_scores_codex":[0.9979933,0.00008525971,0.000487326,0.0005707198,0.0004018691,0.0004615108],"domain_scores_gemma":[0.9986167,0.0001370981,0.0002119651,0.0007260996,0.00005040781,0.0002577377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000385677,0.001219526,0.9880922,0.000004674566,0.001021559,0.005110363,0.0003110884,0.000002046871,0.0007142407,0.000009086737,0.002593896,0.0005356724],"study_design_scores_gemma":[0.0129167,0.001068214,0.9623749,0.0001398899,0.001714024,0.02067702,0.00003796104,0.00001055147,0.0005955994,0.00003294701,0.0002060475,0.0002261484],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961103,0.00108674,0.00003490082,0.001018541,0.00006571694,0.0008960222,0.0001283681,0.0001471019,0.0005123228],"genre_scores_gemma":[0.9963647,0.0003289903,0.0004609116,0.001639769,0.0003025453,0.0001347446,0.000532356,0.00005351118,0.0001824357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02571727,"threshold_uncertainty_score":0.8092614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008174495650932537,"score_gpt":0.2158116786056567,"score_spread":0.2076371829547242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}