{"id":"W2036678630","doi":"10.1016/j.molcel.2014.01.020","title":"GdX/UBL4A Specifically Stabilizes the TC45/STAT3 Association and Promotes Dephosphorylation of STAT3 to Repress Tumorigenesis","year":2014,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dephosphorylation; Biology; Carcinogenesis; Phosphorylation; STAT3; Phosphatase; Cancer research; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005310168,0.0001697799,0.0001748692,0.00003079808,0.00007522431,0.00004378195,0.0002171368,0.0001020638,0.00001456243],"category_scores_gemma":[0.0005792382,0.0001429885,0.00006968932,0.0001196528,0.00005266695,0.000005862708,0.0001730575,0.0000700012,0.000007232638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002683178,"about_ca_system_score_gemma":0.00004145937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007819751,"about_ca_topic_score_gemma":0.00002672738,"domain_scores_codex":[0.9985991,0.00017812,0.0002832016,0.0004220756,0.0002701645,0.000247383],"domain_scores_gemma":[0.998926,0.0000563514,0.0001972447,0.0005567058,0.0001765911,0.00008711174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000798725,0.00006274023,0.004593203,0.00004116822,0.00002866039,0.000001741279,0.00007164697,0.0001708576,0.9906096,0.0005607631,0.0006645943,0.003115174],"study_design_scores_gemma":[0.0003136082,0.0002887902,0.00686708,0.00001073975,0.00003093138,0.000001156466,0.00002749848,0.00006346085,0.9743786,0.0003516681,0.01749581,0.0001706466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717835,0.003455839,0.02295154,0.0003863859,0.00007893561,0.0006078539,0.00005722642,0.00001705526,0.0006617024],"genre_scores_gemma":[0.9951286,0.0001024378,0.004061429,0.0002377743,0.00005531485,0.00005226084,0.00009229776,0.00003174272,0.0002381896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02334509,"threshold_uncertainty_score":0.5830904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004211128796128276,"score_gpt":0.2051682665524906,"score_spread":0.2009571377563623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}