{"id":"W2036804791","doi":"10.1177/095632020501600305","title":"Inhibition of Hepatitis B Virus Gene Expression and Replication by Helioxanthin and its Derivative","year":2005,"lang":"en","type":"article","venue":"Antiviral chemistry & chemotherapy","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Hepatitis B virus; Nucleoside; Virology; Lamivudine; Biology; Nucleoside analogue; DNA; Virus; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007957164,0.0002855525,0.0001215743,0.0001750866,0.00006947763,0.000147262,0.0001648248,0.0001720407,0.0009659735],"category_scores_gemma":[0.00008664619,0.0000892155,0.0001741346,0.00008799275,0.0001284562,0.0001902202,0.0001670492,0.0002779167,0.0002024672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006023576,"about_ca_system_score_gemma":0.00006815769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008499945,"about_ca_topic_score_gemma":0.0001474548,"domain_scores_codex":[0.9999542,0.0000102421,0.00000535968,0.000007275392,0.00001355125,0.000009244213],"domain_scores_gemma":[0.9999635,0.000007098579,0.00001415623,0.000004238581,0.000003710842,0.000007282319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007632596,0.00003054286,0.00009484318,0.00005216164,0.000006184847,0.00006465209,0.000007358738,0.00006437136,0.9960805,0.00006098762,0.00001853911,0.003443496],"study_design_scores_gemma":[0.00006248396,0.002309912,0.004133478,0.00001331623,0.00002943873,0.000707495,0.00002112742,0.000527708,0.9866371,0.0000820148,0.005466084,0.000009889972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830761,0.0110519,0.002958659,0.00008577853,0.00004123646,0.00004176953,0.0001677671,0.00006983108,0.002506945],"genre_scores_gemma":[0.989638,0.004283677,0.002638158,0.00008272432,0.00002659376,0.00004493883,0.0003571227,0.0000129453,0.00291599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009659735,"threshold_uncertainty_score":0.003231525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191378309670658,"score_gpt":0.2687079380968992,"score_spread":0.2567941550001926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}