{"id":"W2036824008","doi":"10.1016/s0002-9440(10)64330-1","title":"Adenoviral Gene Transfer of Interleukin-1 in Combination with Oncostatin M Induces Significant Joint Damage in a Murine Model","year":2003,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"University of Southampton","keywords":"Oncostatin M; Gene transfer; Interleukin 4; Joint (building); Molecular biology; Interleukin 6; Immunology; Gene; Chemistry; Biology; Cytokine; Genetics; Engineering; Structural engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006519003,0.00009987874,0.0005319161,0.0007418373,0.00001414846,0.000003336393,0.00006820489,0.00004285689,0.00003159316],"category_scores_gemma":[0.0001099988,0.00007460101,0.00005554206,0.0004933221,0.0004710579,0.00008912618,0.00001015617,0.000593609,0.000001173781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009944613,"about_ca_system_score_gemma":0.0002713984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009899023,"about_ca_topic_score_gemma":0.00005517244,"domain_scores_codex":[0.9986392,0.0003354444,0.000554616,0.0001210092,0.0001429396,0.0002068282],"domain_scores_gemma":[0.9994258,0.00004679836,0.0001782153,0.0001185608,0.000178422,0.00005225019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001617434,0.001729085,0.08689152,0.00002615466,0.00007682657,0.00200433,0.003392099,0.001049833,0.8879731,0.0008509562,0.00001329504,0.01437533],"study_design_scores_gemma":[0.02172062,0.05930889,0.6620417,0.0005380751,0.0001248613,0.006958949,0.01203468,0.001968276,0.2336426,0.001176954,0.00008253302,0.0004018369],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941953,0.00008329295,0.004594244,0.0005855133,0.00002621487,0.0001413133,0.000002808424,0.000002631202,0.0003686526],"genre_scores_gemma":[0.9964097,0.0001257648,0.003293182,0.0001063821,0.000006263059,0.000006741861,0.000002087205,0.00001228731,0.00003759433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6543306,"threshold_uncertainty_score":0.3042141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02816421193803336,"score_gpt":0.3002506701021875,"score_spread":0.2720864581641541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}