{"id":"W2036842751","doi":"10.1038/mi.2009.6","title":"A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNα responses","year":2009,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"TLR9; Immunology; Biology; Immune system; Toll-Like Receptor 9; Peyer's patch; Innate immune system; Population; Cytokine; CpG Oligodeoxynucleotide; CD11c; Interleukin 10; Peripheral blood mononuclear cell; Cell biology; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001890125,0.0001766351,0.000294705,0.0002188534,0.0001596931,0.0003642231,0.0002163707,0.0002338786,0.002081445],"category_scores_gemma":[0.0001762159,0.0001442377,0.0001780167,0.00008417293,0.0001705298,0.0001562342,0.0001906073,0.0005919441,0.0007858726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009617842,"about_ca_system_score_gemma":0.00008398299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001781974,"about_ca_topic_score_gemma":0.0002320271,"domain_scores_codex":[0.9998817,0.00002102971,0.0000104636,0.0000338118,0.00001822207,0.00003468447],"domain_scores_gemma":[0.9998649,0.00003145254,0.00001634393,0.00002664825,0.00001759159,0.00004293169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173368,0.00002812599,0.0006305588,0.00001670596,0.000002765804,0.000142047,0.0000211565,0.000007381699,0.9977715,0.00004349783,0.00002757062,0.001091483],"study_design_scores_gemma":[0.0002453778,0.001715878,0.05614098,0.0000313088,0.0001357334,0.005493207,0.0004090576,0.001681389,0.9260221,0.0003375804,0.007768388,0.00001898902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970303,0.0008147435,0.0008943945,0.00004984872,0.00003145857,0.0000191352,0.00007072065,0.0000337003,0.001055708],"genre_scores_gemma":[0.9963918,0.0003281221,0.0008942212,0.00006564083,0.00006242458,0.00002798942,0.0002251452,0.00002113385,0.001983327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002081445,"threshold_uncertainty_score":0.006963134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009394017702472312,"score_gpt":0.2208207597648866,"score_spread":0.2114267420624143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}