{"id":"W2036869628","doi":"10.1038/mt.2013.249","title":"Maraba Virus as a Potent Oncolytic Vaccine Vector","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; McMaster University Medical Centre; Ottawa Hospital; University of Guelph; McMaster University","funders":"Canadian Institutes of Health Research; Ontario Institute for Cancer Research; Cancer Research Institute","keywords":"Oncolytic virus; Virology; Adjuvant; Antigen; Heterologous; Immunotherapy; Immune system; Immunity; Melanoma; Virus; Cancer immunotherapy; Vaccination; Biology; Virotherapy; Cancer vaccine; Immunology; Viral vector; Cancer research; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002156749,0.0003123721,0.000234557,0.00009320111,0.000103875,0.00008612723,0.0004930642,0.0001970625,0.001094286],"category_scores_gemma":[0.00003751447,0.000280719,0.0002187623,0.0001989835,0.00005521642,0.000006846541,0.0001084949,0.0001836855,0.001200517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004564478,"about_ca_system_score_gemma":0.0001546744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001950316,"about_ca_topic_score_gemma":0.00004642476,"domain_scores_codex":[0.9980273,0.0001999232,0.0002577367,0.0005677091,0.0003765497,0.0005708029],"domain_scores_gemma":[0.9986156,0.00001132923,0.00007158255,0.0008939317,0.0001722978,0.00023525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00110252,0.0001810646,0.00009117638,0.000004945218,0.0001845857,0.000032792,0.00002819978,0.00004796007,0.9625468,0.00003159883,0.002147129,0.03360119],"study_design_scores_gemma":[0.001924051,0.004481327,0.001142839,0.000007754174,0.000007481375,0.00002966133,0.00001913337,0.00007122372,0.9628747,0.0003865684,0.02870441,0.0003508663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903713,0.005137286,0.0005127742,0.00136472,0.0001148091,0.0008763857,0.000007906126,0.00004358338,0.001571168],"genre_scores_gemma":[0.9916215,0.001326048,0.0002455838,0.004101065,0.0002160714,0.0002835782,0.00008317,0.0001039305,0.002019035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03325032,"threshold_uncertainty_score":0.9999645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01155414276625173,"score_gpt":0.2833689316756323,"score_spread":0.2718147889093806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}