{"id":"W2036903679","doi":"10.4103/2045-8932.109940","title":"Anticipated Classes of New Medications and Molecular Targets for Pulmonary Arterial Hypertension","year":2013,"lang":"en","type":"article","venue":"Pulmonary Circulation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"British Heart Foundation; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research","keywords":"Medicine; Druggability; Context (archaeology); Epigenetics; Bioinformatics; Pharmacology; Computational biology; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003903604,0.0006104745,0.0005279827,0.0008806894,0.0003144038,0.0008814684,0.0005083214,0.001218235,0.02291608],"category_scores_gemma":[0.0003751985,0.0001756437,0.0007454821,0.0004595393,0.0002289629,0.0009171972,0.0005007015,0.002411203,0.00788695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004714363,"about_ca_system_score_gemma":0.0005271354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002517622,"about_ca_topic_score_gemma":0.0010469,"domain_scores_codex":[0.9998361,0.00002760402,0.00001602328,0.00002628554,0.00005675408,0.00003728739],"domain_scores_gemma":[0.9998241,0.0000374583,0.00003446722,0.000008624015,0.00004016819,0.00005527795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008916468,0.000807377,0.0007113494,0.003221602,0.0001027607,0.001244838,0.00008543071,0.0005096978,0.05171645,0.01335375,0.04970963,0.8776454],"study_design_scores_gemma":[0.0004966607,0.002718005,0.003196875,0.0007849251,0.0001541359,0.002993893,0.0000726866,0.000402289,0.01033224,0.007865407,0.970938,0.0000448807],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01609176,0.8746834,0.008100383,0.01856537,0.004856003,0.000444312,0.0020504,0.0004834137,0.07472491],"genre_scores_gemma":[0.06578421,0.8174152,0.0173847,0.01298925,0.004892025,0.0008681673,0.003465031,0.00007136267,0.07713006],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02291608,"threshold_uncertainty_score":0.07666194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03548644718071842,"score_gpt":0.2939679961721567,"score_spread":0.2584815489914383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}