{"id":"W2036944843","doi":"10.1002/cbic.201402202","title":"Recognition of the DNA Minor Groove by Thiazotropsin Analogues","year":2014,"lang":"en","type":"article","venue":"ChemBioChem","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Engineering and Physical Sciences Research Council; Medical Research Council","keywords":"DNA; Chemistry; Stereochemistry; Minor groove; Molecule; Formamide; Nucleobase; Context (archaeology); Base pair; Crystallography; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007518982,0.0001723916,0.0001757825,0.00008318165,0.00008241295,0.0002295621,0.0001876601,0.0001561255,0.0007184029],"category_scores_gemma":[0.0002252758,0.00007953637,0.0001021014,0.00009600935,0.0001443072,0.0001060931,0.00008193386,0.000390169,0.0002641142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002861054,"about_ca_system_score_gemma":0.00009797395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004941916,"about_ca_topic_score_gemma":0.0006445653,"domain_scores_codex":[0.9998883,0.00002767693,0.000006498052,0.00002814416,0.00002986582,0.00001933767],"domain_scores_gemma":[0.9998108,0.00005789639,0.00004408723,0.00001730746,0.00003072523,0.00003919013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003367836,0.00000441108,0.00004400389,0.000007292136,0.000001695145,0.00000912835,0.000008077064,0.00003844238,0.9996019,0.00001510858,0.000005084424,0.000231159],"study_design_scores_gemma":[0.00000638851,0.0001031428,0.0007274273,8.86219e-7,0.000002963347,0.00006699135,0.000008102634,0.0003333694,0.9983768,0.000007871442,0.0003638186,0.000002114888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972454,0.0003159543,0.001689913,0.00002077707,0.000004397183,0.00001001553,0.00004925854,0.0000273429,0.0006367981],"genre_scores_gemma":[0.9975153,0.0001642892,0.00128047,0.00001429787,0.000002229006,0.00001066609,0.0001432047,0.000009550985,0.0008600205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007184029,"threshold_uncertainty_score":0.002403319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00483950635516503,"score_gpt":0.1866820489520654,"score_spread":0.1818425425969004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}