{"id":"W2037046919","doi":"10.1159/000319537","title":"An MRI-Based Semiquantitative Index for the Evaluation of Brain Atrophy and Lesions in Alzheimer’s Disease, Mild Cognitive Impairment and Normal Aging","year":2010,"lang":"en","type":"article","venue":"Dementia and Geriatric Cognitive Disorders","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Health Sciences Centre; Heart and Stroke Foundation; Sunnybrook Health Science Centre; National Research Council Canada; National Research Council Institute for Biodiagnostics","funders":"National Institute on Aging; National Key Research and Development Program of China; University of California, San Diego; Genentech; National Institutes of Health; Eisai; Northern California Institute for Research and Education; National Institute of Biomedical Imaging and Bioengineering; University of California, Los Angeles; U.S. Food and Drug Administration; Dalhousie Medical Research Foundation; Alzheimer's Disease Neuroimaging Initiative; F. Hoffmann-La Roche; Alzheimer's Association; Nova Scotia Health Research Foundation; Medpace; Dalhousie University; GlaxoSmithKline; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Pfizer; Elan; Novartis; Synarc; Dana Foundation; Foundation for the National Institutes of Health","keywords":"Atrophy; Cognitive impairment; Psychology; Alzheimer's disease; Dementia; Cognitive decline; Cognition; Audiology; Neuroscience; Disease; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003159669,0.0005238456,0.0004907718,0.004026364,0.0002448992,0.0007698595,0.0005710092,0.000525777,0.002092323],"category_scores_gemma":[0.005982351,0.00018043,0.0005455883,0.001361508,0.0004549454,0.0009757566,0.0004826613,0.0004423232,0.0005998199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006394665,"about_ca_system_score_gemma":0.0004139664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001037474,"about_ca_topic_score_gemma":0.003095858,"domain_scores_codex":[0.9990289,0.000297,0.0001677353,0.000120854,0.000348832,0.00003672485],"domain_scores_gemma":[0.9972543,0.000848389,0.0008474113,0.0002788288,0.0005764444,0.0001946199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002894985,0.000617729,0.760704,0.0006906233,0.001176762,0.0003329685,0.0006394904,0.00345478,0.04481862,0.001506768,0.007622907,0.1755403],"study_design_scores_gemma":[0.00009670413,0.001258695,0.9736405,0.00007287432,0.0002141726,0.002598776,0.0003174247,0.0108099,0.006185094,0.001528297,0.003187996,0.00008954603],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9513733,0.002774188,0.03083375,0.0002421561,0.0001376166,0.0006324509,0.003920391,0.000409215,0.009676887],"genre_scores_gemma":[0.9520728,0.0004090436,0.04278402,0.0000947634,0.00006578696,0.0004698283,0.002402565,0.00005022164,0.001650894],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.004026364,"threshold_uncertainty_score":0.01671016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02574214266377317,"score_gpt":0.3577336880519364,"score_spread":0.3319915453881633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}