{"id":"W2037046919","doi":"10.1159/000319537","title":"An MRI-Based Semiquantitative Index for the Evaluation of Brain Atrophy and Lesions in Alzheimer’s Disease, Mild Cognitive Impairment and Normal Aging","year":2010,"lang":"en","type":"article","venue":"Dementia and Geriatric Cognitive Disorders","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Health Sciences Centre; Heart and Stroke Foundation; Sunnybrook Health Science Centre; National Research Council Canada; National Research Council Institute for Biodiagnostics","funders":"National Institute on Aging; National Key Research and Development Program of China; University of California, San Diego; Genentech; National Institutes of Health; Eisai; Northern California Institute for Research and Education; National Institute of Biomedical Imaging and Bioengineering; University of California, Los Angeles; U.S. Food and Drug Administration; Dalhousie Medical Research Foundation; Alzheimer's Disease Neuroimaging Initiative; F. Hoffmann-La Roche; Alzheimer's Association; Nova Scotia Health Research Foundation; Medpace; Dalhousie University; GlaxoSmithKline; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Pfizer; Elan; Novartis; Synarc; Dana Foundation; Foundation for the National Institutes of Health","keywords":"Atrophy; Cognitive impairment; Psychology; Alzheimer's disease; Dementia; Cognitive decline; Cognition; Audiology; Neuroscience; Disease; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001462603,0.0002445363,0.0002759845,0.0003744606,0.000285308,0.00005908488,0.00005972751,0.00007194494,0.0001112438],"category_scores_gemma":[0.0003891432,0.0001973217,0.00008516019,0.0003586474,0.0004457016,0.0002083778,0.00006951076,0.0002442952,7.5203e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001124076,"about_ca_system_score_gemma":0.000306759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001671362,"about_ca_topic_score_gemma":0.0005292734,"domain_scores_codex":[0.9980103,0.0002644625,0.0003311636,0.0004965554,0.0005218894,0.0003756171],"domain_scores_gemma":[0.9978231,0.001062988,0.0001438647,0.0001151545,0.0006249342,0.0002299215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002237805,0.0007493008,0.7865158,0.0001496842,0.0005928273,0.000003816041,0.001097402,0.000006599526,0.0004953691,0.0001176024,0.00004418978,0.2079895],"study_design_scores_gemma":[0.0127283,0.001040807,0.9585094,0.0001340062,0.002951239,0.000002144876,0.006166021,0.01719684,0.0004371649,0.0005673926,0.0000460727,0.0002206126],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851805,0.004618829,0.004539181,0.001459428,0.00006377302,0.003803152,0.0001818816,0.0000141463,0.0001390872],"genre_scores_gemma":[0.9979819,0.0005639506,0.0001412959,0.0003580943,0.00004203327,0.0006583154,0.0002233882,0.00002410583,0.000006902827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2077689,"threshold_uncertainty_score":0.8046546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02574214266377317,"score_gpt":0.3577336880519364,"score_spread":0.3319915453881633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}