{"id":"W2037050175","doi":"10.1080/07357900802574660","title":"Pharmacology and Pharmacogenetics of Chemotherapeutic Agents","year":2009,"lang":"en","type":"review","venue":"Cancer Investigation","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Pharmacogenetics; Personalized medicine; Chemotherapeutic drugs; Medicine; Drug; Pharmacology; Precision medicine; Clinical pharmacology; Drug response; Intensive care medicine; Chemotherapy; Bioinformatics; Internal medicine; Biology; Pathology; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005842361,0.0006843029,0.001674357,0.0003567567,0.000149232,0.00001998365,0.0004751268,0.0008169269,0.001123854],"category_scores_gemma":[0.0000214753,0.0006548197,0.0003109902,0.0005359724,0.0005658967,0.00008337473,0.0001175719,0.001043371,0.00003823474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001213514,"about_ca_system_score_gemma":0.0006010092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000116632,"about_ca_topic_score_gemma":0.000001325444,"domain_scores_codex":[0.9966436,0.0008244162,0.001082698,0.0006551059,0.0002489685,0.0005452089],"domain_scores_gemma":[0.997894,0.0002550971,0.0009659224,0.0002363185,0.000159729,0.0004889418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002432109,0.00008497806,0.00005696853,0.005468172,0.0006782943,0.000005971726,0.000239837,0.00005670257,0.002111476,0.00009747093,0.005051129,0.9861247],"study_design_scores_gemma":[0.001141798,0.00005284982,0.00003510972,0.000854373,0.006123442,0.00002368704,0.000005506506,0.0005850096,0.009021444,0.0003859868,0.9812232,0.0005476105],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002783161,0.992187,0.00001068492,0.000172755,0.002529924,0.001269116,0.0003183857,0.00006686608,0.0006620677],"genre_scores_gemma":[0.0005300961,0.994239,0.0001723283,0.003146241,0.001020225,0.000271829,0.0001282394,0.00009216334,0.0003998807],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985577,"threshold_uncertainty_score":0.9997892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3330410630973113,"score_gpt":0.5339622308067224,"score_spread":0.2009211677094112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}