{"id":"W2037098086","doi":"10.1039/b921630h","title":"Nitrones as dipoles for rapid strain-promoted 1,3-dipolar cycloadditions with cyclooctynes","year":2009,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Steacie Institute for Molecular Sciences; University of Ottawa","funders":"","keywords":"Strain (injury); Dipole; Chemistry; Stereochemistry; Computational chemistry; Photochemistry; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003459995,0.0006255893,0.0002567909,0.0002103563,0.000151155,0.0003732608,0.0004214355,0.0002826017,0.002640382],"category_scores_gemma":[0.0002972256,0.0003063318,0.0002182568,0.00017152,0.0003705994,0.0005381323,0.0005306989,0.0007277025,0.0009998769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341502,"about_ca_system_score_gemma":0.0001792664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003047457,"about_ca_topic_score_gemma":0.0008777488,"domain_scores_codex":[0.9998199,0.00002921464,0.00001210335,0.00003378077,0.0000509892,0.00005389643],"domain_scores_gemma":[0.999862,0.0000445947,0.00003068555,0.00001845001,0.00001327254,0.00003106337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403076,0.0000574906,0.0001118758,0.000122603,0.000009628206,0.0001666462,0.00008994479,0.0004655074,0.9914464,0.002585428,0.0003101727,0.004494125],"study_design_scores_gemma":[0.00005096508,0.0002244631,0.0003518019,0.000008300585,0.000007451121,0.000118287,0.0000260027,0.0004854068,0.9932082,0.0001835278,0.00532236,0.00001332602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9603527,0.002284307,0.02063561,0.0002497468,0.0001968872,0.0003153966,0.0003711276,0.0003992283,0.01519501],"genre_scores_gemma":[0.9888738,0.001924408,0.004312292,0.00004884172,0.00002412425,0.0001025789,0.0001947781,0.00006525373,0.004453882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002640382,"threshold_uncertainty_score":0.008832991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02370168104721405,"score_gpt":0.2888882031362979,"score_spread":0.2651865220890839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}