{"id":"W2037125902","doi":"10.1023/b:drug.0000047105.38511.2a","title":"Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98)","year":2004,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; CancerCare Manitoba; Ontario Institute for Cancer Research; AstraZeneca (Canada); Hôpital Notre-Dame; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Doxorubicin; Bolus (digestion); Toxicity; Cancer; Internal medicine; Chemotherapy; Gastroenterology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005743898,0.0001405926,0.0002982467,0.0001198538,0.00003223898,0.00000602899,0.00004293376,0.00002387356,0.0002123048],"category_scores_gemma":[0.00002080925,0.00009881781,0.00001433722,0.0003010961,0.0001046062,0.0001326302,0.00001765519,0.0001054734,0.000003155418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000151057,"about_ca_system_score_gemma":0.0008652645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0025834,"about_ca_topic_score_gemma":0.001452435,"domain_scores_codex":[0.9990452,0.00002732714,0.0002665184,0.0002244639,0.0002855803,0.0001508953],"domain_scores_gemma":[0.9994884,0.00005489356,0.00009170359,0.00009346982,0.0001009775,0.0001705204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01879459,0.02066269,0.8935609,0.0003065514,0.0009742591,0.0001672109,0.02093361,0.01306951,0.004507099,0.0006242787,0.001165944,0.02523338],"study_design_scores_gemma":[0.3593516,0.02475595,0.5931435,0.0008607078,0.0009130781,0.00001779447,0.001702355,0.0001564543,0.0150033,0.002285921,0.001290344,0.0005190796],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974436,0.0002201451,0.00001003646,0.001084618,0.00005113707,0.001030358,0.00001966059,0.00001217471,0.0001282976],"genre_scores_gemma":[0.9967252,0.00002272881,0.001506098,0.0009837609,0.00003623132,0.00009074796,0.000043121,0.00001446562,0.0005776377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.340557,"threshold_uncertainty_score":0.4029673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0233123477740869,"score_gpt":0.3342068102517141,"score_spread":0.3108944624776271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}