{"id":"W2037147152","doi":"10.1042/bsr20140150","title":"Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase of <i>Plasmodium falciparum</i>","year":2014,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Apicoplast; Plasmodium falciparum; Biology; Pyruvate dehydrogenase complex; Dihydrolipoamide dehydrogenase; Biochemistry; Mutant; Malaria; Cell biology; Enzyme; Apicomplexa; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330288,0.0001069272,0.0001458372,0.00002420849,0.00007322548,0.000008955178,0.000169732,0.00008863061,0.000001781105],"category_scores_gemma":[0.0005158443,0.00006954987,0.00006089143,0.0001610257,0.0008137448,0.00000551427,0.000271564,0.00005553282,1.550284e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005282072,"about_ca_system_score_gemma":0.00004956797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000101473,"about_ca_topic_score_gemma":0.000002296139,"domain_scores_codex":[0.9989042,0.00003784813,0.0002815518,0.0003168923,0.0002630044,0.0001965281],"domain_scores_gemma":[0.9992334,0.00001214167,0.0002332725,0.0003513337,0.00009741024,0.00007245431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001452002,0.00001504908,0.02274062,0.0000341643,0.000008331932,5.715162e-7,0.00001323958,0.000001346584,0.9769615,0.00001514556,0.00003262721,0.0001629074],"study_design_scores_gemma":[0.00008126002,0.0000808551,0.03102067,0.00001893438,0.000008292536,0.00005900318,0.000004921178,0.0001368734,0.9679126,0.00004629078,0.0005521519,0.0000781751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992591,0.0001355431,0.0001289073,0.0001252708,0.0001107595,0.000128773,0.0000147303,0.000004199356,0.00009279073],"genre_scores_gemma":[0.9996912,0.00004976829,0.0001065215,0.00004836829,0.00004018823,0.000006106208,0.00001553026,0.000005894397,0.00003639377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009048914,"threshold_uncertainty_score":0.2998277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00623406486030091,"score_gpt":0.2332523262695358,"score_spread":0.2270182614092349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}