{"id":"W2037176629","doi":"10.1128/aac.05336-11","title":"Role of Intracellular Proteases in the Antibiotic Resistance, Motility, and Biofilm Formation of Pseudomonas aeruginosa","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canada Research Chairs; Cystic Fibrosis Canada","keywords":"Proteases; Pseudomonas aeruginosa; Biofilm; Swarming motility; Microbiology; Virulence; Mutant; Protease; Biology; Intracellular; Antibiotic resistance; Antibiotics; Motility; Swarming (honey bee); Bacteria; Cell biology; Enzyme; Gene; Genetics; Quorum sensing; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315702,0.0000976901,0.0001377998,0.00003040303,0.00003328876,0.00001002266,0.00007628534,0.00008221859,0.000006252154],"category_scores_gemma":[0.000005643539,0.0000727278,0.00003451839,0.00005868147,0.000131951,0.000006880468,0.0000281539,0.00003672808,1.74694e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001688638,"about_ca_system_score_gemma":0.00001006871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000929965,"about_ca_topic_score_gemma":0.0000447667,"domain_scores_codex":[0.9994436,0.00004096924,0.0002042375,0.0001478344,0.00004756154,0.0001157793],"domain_scores_gemma":[0.9996947,0.000003747379,0.000111404,0.0001428766,0.00002908299,0.00001821065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001541784,0.0001123329,0.01170883,0.00006785154,0.0000131876,7.062241e-7,0.0005843637,9.072465e-8,0.9848358,0.00004560616,0.0001866562,0.00229037],"study_design_scores_gemma":[0.0004948827,0.00009864823,0.06470151,0.00004778262,0.000008629487,0.000008335363,0.0001530756,0.000009550538,0.9330437,0.00003577432,0.001325647,0.00007251442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991564,0.0001575637,0.00001081003,0.0001237106,0.00001863574,0.0002254713,0.00001766557,0.0000020947,0.0002877216],"genre_scores_gemma":[0.998279,0.0007427633,0.0006365404,0.000272493,0.00002434154,7.270263e-7,0.00001918696,0.000007378768,0.00001758336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05299268,"threshold_uncertainty_score":0.2965754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01121637075670956,"score_gpt":0.2119671735019278,"score_spread":0.2007508027452183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}