{"id":"W2037176629","doi":"10.1128/aac.05336-11","title":"Role of Intracellular Proteases in the Antibiotic Resistance, Motility, and Biofilm Formation of Pseudomonas aeruginosa","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canada Research Chairs; Cystic Fibrosis Canada","keywords":"Proteases; Pseudomonas aeruginosa; Biofilm; Swarming motility; Microbiology; Virulence; Mutant; Protease; Biology; Intracellular; Antibiotic resistance; Antibiotics; Motility; Swarming (honey bee); Bacteria; Cell biology; Enzyme; Gene; Genetics; Quorum sensing; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002505388,0.000573927,0.0003801352,0.0003658046,0.0002463247,0.0004601681,0.0002034854,0.0003337831,0.0002347752],"category_scores_gemma":[0.0003627187,0.0001592329,0.0001945726,0.0002744361,0.0003307857,0.000248804,0.0002948798,0.0003698446,0.0001012519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002627779,"about_ca_system_score_gemma":0.0003616723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241986,"about_ca_topic_score_gemma":0.001335223,"domain_scores_codex":[0.9996972,0.0000692153,0.00003357858,0.00003619754,0.000118381,0.00004540968],"domain_scores_gemma":[0.9998074,0.00004136203,0.00007529177,0.00001885361,0.00002369629,0.00003335083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111664,0.00003548447,0.001687831,0.00002909593,0.000006418476,0.0001134728,0.00002163191,0.0001177023,0.9945121,0.00006212241,0.00001453694,0.00328794],"study_design_scores_gemma":[0.00001887376,0.0004266711,0.03380391,0.00001003966,0.00005261885,0.001365719,0.00009819974,0.001465567,0.9618567,0.0001606111,0.0007286003,0.0000123747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968662,0.001821594,0.000920499,0.00007093088,0.000002996063,0.000006429731,0.00007825677,0.00001009592,0.0002229821],"genre_scores_gemma":[0.99797,0.0007533209,0.0009723241,0.0000129911,0.00000237729,0.000006390287,0.00007108483,0.000004343665,0.000206969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001241986,"threshold_uncertainty_score":0.00246948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01121637075670956,"score_gpt":0.2119671735019278,"score_spread":0.2007508027452183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}