{"id":"W2037181582","doi":"10.1038/cgt.2010.67","title":"Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells","year":2010,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Natural Science Foundation of China","keywords":"Cisplatin; Downregulation and upregulation; In vivo; Cancer research; Apoptosis; Angiogenesis; In vitro; Chemistry; Caspase 3; Biology; Chemotherapy; Programmed cell death; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001052485,0.0004254348,0.0002067964,0.0001838098,0.0000632321,0.000158688,0.0001085198,0.0001188371,0.000770863],"category_scores_gemma":[0.00005427927,0.00008458941,0.0001923206,0.0001129243,0.0001283452,0.0001282801,0.0001333059,0.0003056845,0.0001471159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002164293,"about_ca_system_score_gemma":0.0002202361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004619891,"about_ca_topic_score_gemma":0.000577426,"domain_scores_codex":[0.9999247,0.00001574146,0.000008483784,0.00001318966,0.00001704431,0.0000209118],"domain_scores_gemma":[0.999965,0.000006944925,0.00000806354,0.00000659408,0.000004814142,0.000008610322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001353822,0.00005139388,0.0002317479,0.00003209572,0.000006193344,0.00002936045,0.00000767559,0.0001108256,0.997564,0.00008396076,0.00001955117,0.00172793],"study_design_scores_gemma":[0.00002795189,0.0007966534,0.001242951,0.000002203311,0.0000308031,0.000124784,0.000009530898,0.0007154602,0.9953746,0.00001949178,0.00165333,0.000002145236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956156,0.0008125577,0.002024731,0.00003648295,0.00002679714,0.00004282247,0.0001057802,0.0000702246,0.001264945],"genre_scores_gemma":[0.9950847,0.0006128649,0.002406723,0.00001720304,0.000005732932,0.00003192338,0.0002703195,0.000008163268,0.001562414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000770863,"threshold_uncertainty_score":0.002578795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462275022635097,"score_gpt":0.2725583302666662,"score_spread":0.2579355800403152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}