{"id":"W2037181582","doi":"10.1038/cgt.2010.67","title":"Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells","year":2010,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Natural Science Foundation of China","keywords":"Cisplatin; Downregulation and upregulation; In vivo; Cancer research; Apoptosis; Angiogenesis; In vitro; Chemistry; Caspase 3; Biology; Chemotherapy; Programmed cell death; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515806,0.0002437806,0.0002530435,0.00003302267,0.0001533637,0.0000501466,0.0002535784,0.0001427943,0.00003509329],"category_scores_gemma":[0.000005529206,0.0002219527,0.00007613031,0.00008405245,0.00008974322,0.00001564192,0.00002968553,0.0001662959,0.000001259987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001622531,"about_ca_system_score_gemma":0.0002175257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002004745,"about_ca_topic_score_gemma":0.000331207,"domain_scores_codex":[0.998799,0.00002938208,0.0001450206,0.0005125139,0.0001351597,0.0003788756],"domain_scores_gemma":[0.9991546,0.0000104671,0.0001311753,0.0004558378,0.0001045801,0.0001433271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008696436,0.00007299085,0.0005358486,0.00001064906,0.00005988816,3.33329e-7,0.0001457147,0.00002574088,0.9603332,0.000009066552,0.0005331535,0.03740375],"study_design_scores_gemma":[0.002291913,0.0004557517,0.001828806,0.00000797391,0.00001893243,0.000002988607,0.00001978075,0.00008052445,0.9409013,0.000009406243,0.05406126,0.0003213398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895554,0.003412208,0.004781424,0.00003663487,0.001495735,0.0004951697,0.0001302428,0.00002840243,0.00006483561],"genre_scores_gemma":[0.9936876,0.002220284,0.001158128,0.0003771347,0.001848431,0.000323953,0.00005825782,0.000068841,0.0002573796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0535281,"threshold_uncertainty_score":0.9050969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462275022635097,"score_gpt":0.2725583302666662,"score_spread":0.2579355800403152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}