{"id":"W2037244974","doi":"10.1530/joe-13-0055","title":"Maternal protein restriction leads to enhanced hepatic gluconeogenic gene expression in adult male rat offspring due to impaired expression of the liver X receptor","year":2013,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Offspring; Biology; Liver X receptor; Glucose homeostasis; Gluconeogenesis; Impaired glucose tolerance; Gene expression; Pregnancy; Nuclear receptor; Diabetes mellitus; Insulin resistance; Gene; Medicine; Genetics; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001595447,0.0001529211,0.0004652039,0.0003459056,0.00006164102,0.000008947408,0.0002069906,0.0001035534,0.0003036839],"category_scores_gemma":[0.0002399936,0.0001008264,0.00009506803,0.0002255219,0.0000319719,0.0001234786,0.0001190223,0.0003887623,0.00005818953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002186792,"about_ca_system_score_gemma":0.0002108458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002161797,"about_ca_topic_score_gemma":0.00004549893,"domain_scores_codex":[0.9980895,0.0001807879,0.0008242354,0.0001918614,0.0003135122,0.0004000961],"domain_scores_gemma":[0.9987227,0.00003710329,0.0004600496,0.0002443942,0.0003256192,0.0002101863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006700004,0.0001074895,0.03835714,0.0001165406,0.00001083045,0.00007144572,0.0005221029,0.00001794097,0.9576337,0.00004369799,0.0005672337,0.001881829],"study_design_scores_gemma":[0.001272911,0.0005524821,0.2126131,0.0008739985,0.00001023507,0.000536651,0.00009574996,0.000007091212,0.7838398,0.0000745311,0.00005124956,0.00007220182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996105,0.0001575392,0.00055173,0.001634835,0.0005305147,0.0009130907,0.00000125588,0.000009963359,0.00009609049],"genre_scores_gemma":[0.9857949,0.001986071,0.01144388,0.0003591987,0.0001942642,0.00006049825,7.838586e-7,0.00001833039,0.0001420562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.174256,"threshold_uncertainty_score":0.4111582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01638901953552484,"score_gpt":0.2656422931655577,"score_spread":0.2492532736300328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}