{"id":"W2037336019","doi":"10.1074/jbc.m106428200","title":"PSTPIP Is a Substrate of PTP-PEST and Serves as a Scaffold Guiding PTP-PEST Toward a Specific Dephosphorylation of WASP","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Dephosphorylation; PEST analysis; Substrate (aquarium); Scaffold; Phosphorylation; Biology; Cell biology; Computer science; Ecology; Botany; Phosphatase; Programming language","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003190895,0.0002285465,0.0004271565,0.0000303879,0.00004136076,0.00002234591,0.0003063113,0.000313296,0.000311876],"category_scores_gemma":[0.0002979542,0.0001783588,0.0002101822,0.0001333878,0.0002570433,0.00001407988,0.0001255533,0.0001389053,0.000002859458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001959018,"about_ca_system_score_gemma":0.00004047666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001017042,"about_ca_topic_score_gemma":5.188762e-7,"domain_scores_codex":[0.9984667,0.00004186493,0.0007531705,0.0002883635,0.0002137784,0.0002360719],"domain_scores_gemma":[0.9985378,0.00004276213,0.0007707286,0.0002475224,0.0002513172,0.0001499116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002457284,0.0001516355,0.007361114,0.0001114084,0.00007709379,0.00002301568,0.00004041415,0.000007713516,0.9897624,0.00004448193,0.0009429585,0.001232041],"study_design_scores_gemma":[0.0007026449,0.0006030923,0.005319685,0.0001222503,0.00003052708,0.0002606708,0.0001153289,0.00001632975,0.9905691,0.0002243989,0.001847133,0.0001888566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649702,0.03411483,0.00008044958,0.0002483608,0.00005156879,0.00009165004,0.00006243541,0.000005308999,0.0003751447],"genre_scores_gemma":[0.9936877,0.004740684,0.001174427,0.00006447105,0.0002101137,0.000003290331,0.00002865835,0.00001364895,0.00007698429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02937415,"threshold_uncertainty_score":0.7273262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04682275631390818,"score_gpt":0.2502022191746073,"score_spread":0.2033794628606992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}