{"id":"W2037350894","doi":"10.1016/j.bbamem.2010.02.006","title":"Pore-forming properties of the Bacillus thuringiensis toxin Cry9Ca in Manduca sexta brush border membrane vesicles","year":2010,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Manduca sexta; Bacillus thuringiensis; Brush border; Vesicle; Manduca; Biochemistry; Mutant; Toxin; Cry1Ac; Biology; Cleavage (geology); Midgut; Biophysics; Protease; Membrane; Microbiology; Chemistry; Enzyme; Larva; Bacteria; Botany; Transgene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002282084,0.0001077754,0.0001374364,0.0001647475,0.0002451543,0.000418223,0.0001639295,0.0002642603,0.0006457652],"category_scores_gemma":[0.0004239838,0.0001134733,0.0001960869,0.0001176866,0.0002270945,0.0004896769,0.0001645133,0.0005442931,0.00017001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005307936,"about_ca_system_score_gemma":0.0001783959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001448795,"about_ca_topic_score_gemma":0.0007029836,"domain_scores_codex":[0.9999233,0.00001008473,0.000004800052,0.00001668571,0.00002256057,0.00002260825],"domain_scores_gemma":[0.999824,0.00005869214,0.00003066095,0.00001515327,0.00004014639,0.0000313701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001338107,0.00001337794,0.0004343612,0.00002174245,0.000007423016,0.00003449497,0.00007109827,0.0001053979,0.9980787,0.0005206401,0.00004085471,0.0005380521],"study_design_scores_gemma":[0.00002068753,0.0001154315,0.01058101,0.00001024677,0.00001650147,0.0002140249,0.0001123143,0.003659296,0.9840676,0.0002761739,0.0009108221,0.00001591274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987206,0.0002678639,0.0004626782,0.00004623754,0.000005949518,0.000003696335,0.00009238873,0.00000987058,0.0003907794],"genre_scores_gemma":[0.9990434,0.0001146075,0.0001853481,0.00001416869,0.000002859048,0.000002637005,0.0001399108,0.000005962496,0.0004911286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001448795,"threshold_uncertainty_score":0.003851175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008853306514933226,"score_gpt":0.2351783707003791,"score_spread":0.2263250641854459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}