{"id":"W2037350894","doi":"10.1016/j.bbamem.2010.02.006","title":"Pore-forming properties of the Bacillus thuringiensis toxin Cry9Ca in Manduca sexta brush border membrane vesicles","year":2010,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Manduca sexta; Bacillus thuringiensis; Brush border; Vesicle; Manduca; Biochemistry; Mutant; Toxin; Cry1Ac; Biology; Cleavage (geology); Midgut; Biophysics; Protease; Membrane; Microbiology; Chemistry; Enzyme; Larva; Bacteria; Botany; Transgene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002626435,0.0004327777,0.0004103364,0.000164033,0.0001771079,0.00007130013,0.000790571,0.0003529365,0.00002161634],"category_scores_gemma":[0.00009169725,0.0003130092,0.0002836502,0.0005192821,0.0005581714,0.00002414497,0.0003453524,0.0003115067,0.000006550787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001568147,"about_ca_system_score_gemma":0.0002282423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001426677,"about_ca_topic_score_gemma":0.0005783026,"domain_scores_codex":[0.9977998,0.0001048362,0.0005455441,0.000638006,0.0003518189,0.0005600001],"domain_scores_gemma":[0.9984271,0.00002022662,0.0002750969,0.001034774,0.0001448035,0.0000980293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001962406,0.0001874579,0.00006088631,0.0001864088,0.00008512526,0.000002289785,0.0004743799,0.000006314083,0.997961,0.00005919678,0.0001218144,0.0006588913],"study_design_scores_gemma":[0.0006337221,0.0001327511,0.007628673,0.00009381965,0.00004585215,0.00001718435,0.0002120821,0.000039615,0.986702,0.00003748367,0.004010781,0.0004460152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968901,0.0003735253,0.000001630603,0.001223619,0.0004225854,0.0004258259,0.0000694501,0.00002775242,0.0005654914],"genre_scores_gemma":[0.9978597,0.0004285924,0.0002661865,0.0003524244,0.0003622316,0.00003404021,0.00006677575,0.00006282576,0.0005672862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01125897,"threshold_uncertainty_score":0.9999322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008853306514933226,"score_gpt":0.2351783707003791,"score_spread":0.2263250641854459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}